Evidence map›Paper›PMID 34579113›Full record

ArticleNutrients2021

Gut Microbiome Composition and Metabolic Status Are Differently Affected by Early Exposure to Unhealthy Diets in a Rat Model.

Paolo De Marco, Ana C Henriques, Rui Azevedo, Susana I Sá, Armando Cardoso, Bruno Fonseca, Joana Barbosa, Sandra Leal

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Paolo De MarcoTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, CESPU, CRL, 4585-116 Gandra, Portugal.
Ana C HenriquesTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, CESPU, CRL, 4585-116 Gandra, Portugal.
Rui AzevedoTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, CESPU, CRL, 4585-116 Gandra, Portugal.
Susana I SáCenter for Health Technology and Services Research (CINTESIS), Rua Dr. Plácido da Costa, 4200-450 Porto, Portugal.ORCID 0000-0002-5078-980X
Armando CardosoCenter for Health Technology and Services Research (CINTESIS), Rua Dr. Plácido da Costa, 4200-450 Porto, Portugal.
Bruno FonsecaUCIBIO-Applied Molecular Biosciences Unit, Biochemistry Laboratory, Biological Sciences Department, Faculty of Pharmacy, University of Porto, Rua Jorge de Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0000-0002-8873-5591
Joana BarbosaTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, CESPU, CRL, 4585-116 Gandra, Portugal.ORCID 0000-0003-2236-1029
Sandra LealTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, CESPU, CRL, 4585-116 Gandra, Portugal.ORCID 0000-0002-6762-4534
Universidade do Porto · PTCooperativa de Ensino Superior Politécnico e Universitário · PT

Funding

CESPU-IINFACTS FoodMicrobiome_CESPU_2017European Regional Development Fund POCI-01-0145-FEDER-007746Fundação para a Ciência e a Tecnologia UID/IC/4255/2013
6 · The paper itself

Abstract

Childhood is a critical stage of development during which diet can have profound influence on the microbiota-host interactions, leading to potentially lifelong impacts. This study aimed to investigate whether the consumption of cafeteria diet (CAFD) and sugary drinks during early rat life alters the structure of the gut microbial community and the metabolic activity. Four-week-old male Wistar rats (

Indexed as

Animal FeedAnimalsBacteriaBody CompositionDietEnergy MetabolismFecesGastrointestinal MicrobiomeMaleRatsRats, WistarRNA, BacterialRNA, Ribosomal, 16SRNA, BacterialRNA, Ribosomal, 16Scafeteria diethigh-sugar dietmetabolic dysregulationmicrobiotayoung animal

Identifiers

PMID34579113
PMCPMC8469890
OpenAlexW3200794417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.