Evidence map›Paper›PMID 34579110›Full record

ReviewNutrients2021

Vitamin B6 in Health and Disease.

Kamilla Stach, Wojciech Stach, Katarzyna Augoff

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 1 pooled it
20.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 1 synthesis or guideline pooled it, 207 citations in OpenAlex.

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  20. Role of Vitamin B₆ in Testosterone Synthesis.The world journal of men's health · 2026
    Review

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kamilla StachDepartment of Medical Biochemistry, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Wojciech StachDepartment of Medical Biochemistry, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Katarzyna AugoffDepartment of Surgical Education, Wroclaw Medical University, 50-668 Wroclaw, Poland.
Wroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin B6 is a fascinating molecule involved in the vast majority of changes in the human body because it is a coenzyme involved in over 150 biochemical reactions. It is active in the metabolism of carbohydrates, lipids, amino acids, and nucleic acids, and participates in cellular signaling. It is an antioxidant and a compound with the ability to lower the advanced glycation end products (AGE) level. In this review, we briefly summarize its involvement in biochemical pathways and consider whether its deficiency may be associated with various diseases such as diabetes, heart disease, cancer, or the prognosis of COVID-19.

Indexed as

Nutritional Physiological PhenomenaNutritional StatusCOVID-19Diabetes MellitusHeart DiseasesHumansNeoplasmsRisk FactorsSARS-CoV-2Signal TransductionVitamin B 6Vitamin B 6 DeficiencyVitamin B 6cancercardiovascular diseaseCOVID-19diabetesimmune systempyridoxal 5′-phosphate (PLP)vitamin B6

Identifiers

PMID34579110
PMCPMC8467949
OpenAlexW3200747207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.