Evidence map›Paper›PMID 34579108›Full record

ArticleNutrients2021

Quality of Life and Psychological Disorders in Coeliac Disease: A Prospective Multicentre Study.

Cristina Canova, Isabella Rosato, Ilaria Marsilio, Flavio Valiante, Valerio Zorzetto, Giovanni Cataudella, Anna D'Odorico, Fabiana Zingone

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Life Challenges and Quality of Life of People Living With Coeliac Disease: Time of Diagnosis Matters.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Article
  10. Physical and psychological symptoms and survey importance in celiac disease.World journal of gastrointestinal endoscopy · 2024
    Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Challenges faced by celiac disease patients during the COVID-19 pandemic.Gastroenterology and hepatology from bed to bench · 2023
    Article
  18. Review article: Systemic consequences of coeliac disease.Alimentary pharmacology & therapeutics · 2022
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Cristina CanovaUnit of Biostatistics, Epidemiology and Public Health, Department of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padua, 35131 Padova, Italy.
Isabella RosatoUnit of Biostatistics, Epidemiology and Public Health, Department of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padua, 35131 Padova, Italy.
Ilaria MarsilioDepartment of Surgery, Oncology, Gastroenterology, University of Padua, 35124 Padova, Italy.ORCID 0000-0003-1737-4183
Flavio ValianteGastroenterology and Digestive Endoscopy Unit, ULSS 1 Dolomiti, Santa Maria del Prato Hospital, 32032 Feltre, Italy.
Valerio ZorzettoGastroenterology and Endoscopy Unit, ULSS 9, 37045 Legnago, Italy.
Giovanni CataudellaGastroenterology and Endoscopy Unit, San Bortolo Hospital, 36100 Vicenza, Italy.
Anna D'OdoricoDepartment of Surgery, Oncology, Gastroenterology, University of Padua, 35124 Padova, Italy.
Fabiana ZingoneDepartment of Surgery, Oncology, Gastroenterology, University of Padua, 35124 Padova, Italy.ORCID 0000-0003-1133-1502
University of Padua · ITHospital of Prato · ITOspedale San Bortolo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coeliac disease (CeD) has been associated with psychological disorders and reduced quality of life. Our prospective study evaluated the changes in the quality of life, anxiety and depression in CeD patients up to two years after diagnosis. We recruited adult patients residing in the Veneto region with a new diagnosis of CeD. Several validated questionnaires were administered to measure quality of life, psychological symptoms and adherence to a gluten-free diet (GFD) at the time of diagnosis and after 1 and 2 years. Ninety-three patients reached the 1-year follow-up (81.7% were females with a median age at diagnosis of 35 years), and 55 patients reached the 2-year follow-up. We observed a significant improvement in quality of life, anxiety and depression scores at 1 year after diagnosis, particularly in patients who complied with a GFD. The improvements among classical CeD patients were similar to those observed in nonclassical patients except for anxiety, which improved only in patients with a classical presentation at diagnosis. Age, sex and other disease factors did not affect the change in quality of life (QoL) or other mood disorders. Most of the improvements measured 1 year after diagnosis and 2 years after diagnosis were not significant. In conclusion, QoL and mood disorders must be considered, and psychological counselling should be used when needed.

Indexed as

Anxiety DisordersDiet, Gluten-FreeQuality of LifeAdultCeliac DiseaseFemaleHumansMalePatient ComplianceSurveys and Questionnairesanxietyceliac diseasedepressiondietary compliancequality of life

Identifiers

PMID34579108
PMCPMC8470791
OpenAlexW3200275349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.