Evidence map›Paper›PMID 34579049›Full record

Trial reportNutrients2021

A Randomised, Controlled Trial: Effect of a Multi-Strain Fermented Milk on the Gut Microbiota Recovery after

Eric Guillemard, Marion Poirel, Florent Schäfer, Laurent Quinquis, Caroline Rossoni, Christian Keicher, Frank Wagner, Hania Szajewska, Frédéric Barbut, Muriel Derrien and 1 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05662514 (Effect of Probiotics on Gut Microbiota During the Helicobacter Pylori Eradication), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05662514 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effect of Probiotics on Gut Microbiota During the Helicobacter Pylori Eradication: a Randomized Double-blind Placebo-controlled Trial

TypeinterventionalSponsorQilu Hospital of Shandong UniversityRan2023 to 2024Enrolled100ConditionsHelicobacter Pylori Infection, Gut MicrobiotaArmsBifidobacterium animalis subsp. lactis BLa80, Placebo
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Efficacy of probiotics pretreatment inAnnals of medicine · 2025
    Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
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  15. Article
  16. Review
  17. High-Salt Diet ExacerbatesJournal of personalized medicine · 2023
    Review
  18. Helicobacter pylori infection.Nature reviews. Disease primers · 2023
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Eric GuillemardDanone Nutricia Research, Department of Innovation Science and Nutrition, 91767 Palaiseau, France.
Marion PoirelDanone Nutricia Research, Department of Innovation Science and Nutrition, 91767 Palaiseau, France.
Florent SchäferDanone Nutricia Research, Department of Innovation Science and Nutrition, 91767 Palaiseau, France.ORCID 0000-0001-6816-5731
Laurent QuinquisDanone Nutricia Research, Department of Innovation Science and Nutrition, 91767 Palaiseau, France.
Caroline RossoniDanone Nutricia Research, Department of Innovation Science and Nutrition, 91767 Palaiseau, France.
Christian KeicherCharité Research Organisation GmbH, 10117 Berlin, Germany.
Frank WagnerCharité Research Organisation GmbH, 10117 Berlin, Germany.
Hania SzajewskaDepartment of Paediatrics, Medical University of Warsaw, 02-091 Warszawa, Poland.ORCID 0000-0002-4596-2874
Frédéric BarbutINSERM S-1139, Université de Paris, 75006 Paris, France.
Muriel DerrienDanone Nutricia Research, Department of Innovation Science and Nutrition, 91767 Palaiseau, France.ORCID 0000-0001-8841-9153
Peter MalfertheinerDepartment of Gastroenterology, Hepatology and Infectious Diseases, Magdeburg Clinic, OVGU University, 39120 Magdeburg, Germany.
Danone (France) · FRCharité - Universitätsmedizin Berlin · DEInserm · FRLMU Klinikum · DEMedical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cultured Milk ProductsGastrointestinal MicrobiomeAdultAgedAnti-Bacterial AgentsDiarrheaDouble-Blind MethodFecesFemaleHelicobacter InfectionsHelicobacter pyloriHumansMaleMiddle AgedProbioticsTreatment OutcomeAnti-Bacterial Agentsantibiotic associated diarrheaantibioticsgut microbiotaHelicobacter pylorirecoveryshort chain fatty acids

Identifiers

PMID34579049
PMCPMC8466689
OpenAlexW3199400248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.