Evidence map›Paper›PMID 34579038›Full record

ArticleNutrients2021

Dieckol-Attenuated High-Fat Diet Induced Muscle Atrophy by Modulating Muscular Deposition of Lipid Droplets.

Kyung-A Byun, Seyeon Oh, Myeongjoo Son, Seung Eon Oh, Chul-Hyun Park, Kuk Hui Son, Kyunghee Byun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kyung-A ByunDepartment of Anatomy&Cell Biology, Gachon University College of Medicine, Incheon 21936, Korea.ORCID 0000-0001-7486-9137
Seyeon OhFunctional Cellular Networks Laboratory, Department of Medicine, Graduate School and Lee Gil Ya Cancer and Diabetes Institute, College of Medicine, Gachon University, Incheon 21999, Korea.
Myeongjoo SonDepartment of Anatomy&Cell Biology, Gachon University College of Medicine, Incheon 21936, Korea.ORCID 0000-0002-9104-3991
Seung Eon OhFunctional Cellular Networks Laboratory, Department of Medicine, Graduate School and Lee Gil Ya Cancer and Diabetes Institute, College of Medicine, Gachon University, Incheon 21999, Korea.
Chul-Hyun ParkDepartment of Thoracic and Cardiovascular Surgery, Gachon University Gil Medical Center, Gachon University, Incheon 21565, Korea.
Kuk Hui SonDepartment of Thoracic and Cardiovascular Surgery, Gachon University Gil Medical Center, Gachon University, Incheon 21565, Korea.
Kyunghee ByunDepartment of Anatomy&Cell Biology, Gachon University College of Medicine, Incheon 21936, Korea.
Gachon University · KRGachon University Gil Medical Center · KR

Funding

Ministry of SMEs and Startups S2913152
6 · The paper itself

Abstract

An excessive fat diet induces intramuscular fat deposition that accumulates as a form of lipid droplet (LD) and leads to lipotoxicity, including muscle atrophy or decreasing muscle strength. Lipotoxicity depends on the number of LDs, subcellular distribution (intermyofibrillar, IMF, LDs or subsarcolemmal, SS), and fiber type-specific differences (type I or type II fiber) as well as the size of LD.

Indexed as

AnimalsBenzofuransDietary FatsDiet, High-FatGene Expression RegulationLipid DropletsLipid MetabolismMaleMiceMice, Inbred C57BLMuscle, SkeletalMuscle StrengthMuscular AtrophyPerilipin-1PhaeophyceaePPAR alphaBenzofuransdieckolDietary FatsPerilipin-1Plin1 protein, mousePPAR alphalipid dropletlipotoxicitymuscle atrophyperilipin2

Identifiers

PMID34579038
PMCPMC8467349
OpenAlexW3199802273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.