Evidence map›Paper›PMID 34578985›Full record

ArticleNutrients2021

Plant-Derived and Dietary Hydroxybenzoic Acids-A Comprehensive Study of Structural, Anti-/Pro-Oxidant, Lipophilic, Antimicrobial, and Cytotoxic Activity in MDA-MB-231 and MCF-7 Cell Lines.

Monika Kalinowska, Ewelina Gołębiewska, Grzegorz Świderski, Sylwia Męczyńska-Wielgosz, Hanna Lewandowska, Anna Pietryczuk, Adam Cudowski, Aleksander Astel, Renata Świsłocka, Mariola Samsonowicz and 3 more

Abstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Article
  2. Review
  3. EngineeringMetabolic engineering communications · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Novel p-Hydroxybenzoic Acid Derivative Isolated fromAntibiotics (Basel, Switzerland) · 2025
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Monika KalinowskaDepartment of Chemistry, Biology and Biotechnology, Bialystok University of Technology, Wiejska 45E Street, 15-351 Bialystok, Poland.ORCID 0000-0002-0839-9891
Ewelina GołębiewskaDepartment of Chemistry, Biology and Biotechnology, Bialystok University of Technology, Wiejska 45E Street, 15-351 Bialystok, Poland.ORCID 0000-0002-5039-9537
Grzegorz ŚwiderskiDepartment of Chemistry, Biology and Biotechnology, Bialystok University of Technology, Wiejska 45E Street, 15-351 Bialystok, Poland.ORCID 0000-0003-4442-6348
Sylwia Męczyńska-WielgoszInstitute of Nuclear Chemistry and Technology, 16 Dorodna Street, 03-195 Warsaw, Poland.ORCID 0000-0002-9475-983X
Hanna LewandowskaInstitute of Nuclear Chemistry and Technology, 16 Dorodna Street, 03-195 Warsaw, Poland.ORCID 0000-0002-1960-1071
Anna PietryczukDepartment of Water Ecology, Faculty of Biology, University of Bialystok, Ciolkowskiego 1J Street, 15-245 Bialystok, Poland.
Adam CudowskiDepartment of Water Ecology, Faculty of Biology, University of Bialystok, Ciolkowskiego 1J Street, 15-245 Bialystok, Poland.
Aleksander AstelEnvironmental Chemistry Research Unit, Institute of Biology and Earth Sciences, Pomeranian University in Słupsk, Arciszewskiego 22a Street, 76-200 Słupsk, Poland.ORCID 0000-0003-2077-7020
Renata ŚwisłockaDepartment of Chemistry, Biology and Biotechnology, Bialystok University of Technology, Wiejska 45E Street, 15-351 Bialystok, Poland.ORCID 0000-0001-7034-9126
Mariola SamsonowiczDepartment of Chemistry, Biology and Biotechnology, Bialystok University of Technology, Wiejska 45E Street, 15-351 Bialystok, Poland.ORCID 0000-0003-4981-0779
Anna Barbara ZłowodzkaFaculty of Chemistry, Warsaw University of Technology, Noakowskiego 3 Street, 00-664 Warszawa, Poland.
Waldemar PriebeDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, 1901 East Rd., Houston, TX 77054, USA.
Włodzimierz LewandowskiInstitute of Agricultural and Food Biotechnology-State Research Institute, Rakowiecka 36 Street, 02-532 Warsaw, Poland.

Funding

Narodowe Centrum Nauki UMO-2018/31/B/NZ7/03083
6 · The paper itself

Abstract

Seven derivatives of plant-derived hydroxybenzoic acid (HBA)-including 2,3-dihydroxybenzoic (2,3-DHB, pyrocatechuic), 2,4-dihydroxybenzoic (2,4-DHB, β-resorcylic), 2,5-dihydroxybenzoic (2,5-DHB, gentisic), 2,6-dihydroxybenzoic (2,6-DHB, γ-resorcylic acid), 3,4-dihydroxybenzoic (3,4-DHB, protocatechuic), 3,5-dihydroxybenzoic (3,5-DHB, α-resorcylic), and 3,4,5-trihydroxybenzoic (3,4,5-THB, gallic) acids-were studied for their structural and biological properties. Anti-/pro-oxidant properties were evaluated by using DPPH

Indexed as

Anti-Infective AgentsAntioxidantsCell Line, TumorCytotoxinsHumansHydroxybenzoatesMCF-7 CellsPlant ExtractsReactive Oxygen SpeciesStructure-Activity RelationshipAnti-Infective AgentsAntioxidantsCytotoxinsHydroxybenzoatesPlant ExtractsReactive Oxygen Speciesantimicrobialantioxidanthydroxybenzoic acidslipophilicMCF-7MDA-MB-231quantum chemical calculationsSARspectroscopy

Identifiers

PMID34578985
PMCPMC8466373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.