Evidence map›Paper›PMID 34578958›Full record

ArticleNutrients2021

Longitudinal Plasma Metabolomics Profile in Pregnancy-A Study in an Ethnically Diverse U.S. Pregnancy Cohort.

Susanna D Mitro, Jing Wu, Mohammad L Rahman, Yaqi Cao, Yeyi Zhu, Zhen Chen, Liwei Chen, Mengying Li, Stefanie N Hinkle, Andrew A Bremer and 6 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  17. Serum Amino Acid Variations in Obesity and Gestational Diabetes During Pregnancy.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  18. Article
  19. Article
  20. Metabolomic prediction of severe maternal and newborn complications in preeclampsia.Metabolomics : Official journal of the Metabolomic Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 1 country.

Susanna D MitroEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20817, USA.
Jing WuGlotech, Inc., Rockville, MD 20850, USA.
Mohammad L RahmanDepartment of Population Medicine and Harvard Pilgrim Health Care Institute, Harvard Medical School, Boston, MA 02115, USA.
Yaqi CaoDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Yeyi ZhuDivision of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA.
Zhen ChenBiostatistics and Bioinformatics Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20817, USA.
Liwei ChenDepartment of Epidemiology, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA 90095, USA.
Mengying LiEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20817, USA.ORCID 0000-0002-3713-1683
Stefanie N HinkleEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20817, USA.
Andrew A BremerPediatric Growth and Nutrition Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20817, USA.
Natalie L WeirDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA.
Michael Y TsaiDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA.
Yiqing SongDepartment of Epidemiology, Indiana University Richard M. Fairbanks School of Public Health, Indianapolis, IN 46202, USA.ORCID 0000-0002-2097-7332
Katherine L GrantzEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20817, USA.
Bizu GelayeDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Cuilin ZhangEpidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20817, USA.
National Institutes of Health · USHarvard University · USUniversity of Minnesota · USGlotech (United States) · USIndiana University – Purdue University Indianapolis · USKaiser Permanente · USUniversity of California, Los Angeles · USUniversity of Pennsylvania · US

Funding

Fetal Programming of Growth and Obesity: A Metabolomics ApproachK01DK120807 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI ZHU, YEYI · 2019 to 2022
$699k
Eunice Kennedy Shriver National Institute of Child Health and Human Development Intramural fundingNIDDK NIH HHS K01 DK120807NIDDK NIH HHS K01DK120807
6 · The paper itself

Abstract

Amino acids, fatty acids, and acylcarnitine metabolites play a pivotal role in maternal and fetal health, but profiles of these metabolites over pregnancy are not completely established. We described longitudinal trajectories of targeted amino acids, fatty acids, and acylcarnitines in pregnancy. We quantified 102 metabolites and combinations (37 fatty acids, 37 amino acids, and 28 acylcarnitines) in plasma samples from pregnant women in the

Indexed as

AdolescentAdultAmino AcidsBody Mass IndexCarnitineFatty AcidsFemaleHumansMaleMetabolomicsPregnancyPregnancy TrimestersProspective StudiesRacial GroupsUnited StatesYoung AdultacylcarnitineAmino AcidsCarnitineFatty Acidsacylcarnitinesamino acidsfatty acidslongitudinalnon-linearpregnancytargeted metabolomics

Identifiers

PMID34578958
PMCPMC8471130
OpenAlexW3196338187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.