Evidence map›Paper›PMID 34578944›Full record

ArticleNutrients2021

Lower Dietary Intake of Plant Protein Is Associated with Genetic Risk of Diabetes-Related Traits in Urban Asian Indian Adults.

Sooad Alsulami, Dhanasekaran Bodhini, Vasudevan Sudha, Coimbatore Subramanian Shanthi Rani, Rajendra Pradeepa, Ranjit Mohan Anjana, Venkatesan Radha, Julie A Lovegrove, Rajagopal Gayathri, Viswanathan Mohan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Optimizing Nutrition Strategies for Diabetes Management in India: An Expert Opinion.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Sooad AlsulamiHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6DZ, UK.
Dhanasekaran BodhiniDepartment of Molecular Genetics, Madras Diabetes Research Foundation, Chennai 603103, India.ORCID 0000-0001-7194-0639
Vasudevan SudhaDepartment of Foods, Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai 600086, India.
Coimbatore Subramanian Shanthi RaniDepartment of Clinical Epidemiology, Madras Diabetes Research Foundation, Chennai 600086, India.
Rajendra PradeepaDepartment of Diabetology, Madras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialities Centre, WHO Collaborating Centre for Non-Communicable Diseases Prevention and Control, ICMR Centre for Advanced Research on Diabetes, Gopalapuram, Chennai 600086, India.
Ranjit Mohan AnjanaDepartment of Diabetology, Madras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialities Centre, WHO Collaborating Centre for Non-Communicable Diseases Prevention and Control, ICMR Centre for Advanced Research on Diabetes, Gopalapuram, Chennai 600086, India.
Venkatesan RadhaDepartment of Molecular Genetics, Madras Diabetes Research Foundation, Chennai 603103, India.
Julie A LovegroveHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6DZ, UK.ORCID 0000-0001-7633-9455
Rajagopal GayathriDepartment of Foods, Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai 600086, India.
Viswanathan MohanDepartment of Diabetology, Madras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialities Centre, WHO Collaborating Centre for Non-Communicable Diseases Prevention and Control, ICMR Centre for Advanced Research on Diabetes, Gopalapuram, Chennai 600086, India.ORCID 0000-0001-5038-6210
Karani Santhanakrishnan VimaleswaranHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6DZ, UK.ORCID 0000-0002-8485-8930
Madras Diabetes Research Foundation · INUniversity of Reading · GBKing Abdulaziz University · SA

Funding

Medical Research Council MR/S024778/1
6 · The paper itself

Abstract

The increasing prevalence of type 2 diabetes among South Asians is caused by a complex interplay between environmental and genetic factors. We aimed to examine the impact of dietary and genetic factors on metabolic traits in 1062 Asian Indians. Dietary assessment was performed using a validated semi-quantitative food frequency questionnaire. Seven single nucleotide polymorphisms (SNPs) from the Transcription factor 7-like 2 and fat mass and obesity-associated genes were used to construct two metabolic genetic risk scores (GRS): 7-SNP and 3-SNP GRSs. Both 7-SNP GRS and 3-SNP GRS were associated with a higher risk of T2D (

Indexed as

AdultAsian PeopleDiabetes Mellitus, Type 2DietFemaleGenetic Predisposition to DiseaseHumansIndiaMaleMiddle AgedPlant ProteinsPolymorphism, Single NucleotideRiskUrban PopulationPlant Proteinsdietary protein intakegene–diet interactiongenetic risk scoremetabolic traitsT2Durban Asian Indian

Identifiers

PMID34578944
PMCPMC8466015
OpenAlexW3196443831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.