Evidence map›Paper›PMID 34578904›Full record

ArticleNutrients2021

Metabolome Characteristics of Liver Autophagy Deficiency under Starvation Conditions in Infancy.

Kazuhito Sekiguchi, Hiroaki Miyahara, Masanori Inoue, Kyoko Kiyota, Kumiko Sakai, Toshikatsu Hanada, Kenji Ihara

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kazuhito SekiguchiDepartment of Pediatrics, Oita University Faculty of Medicine, Yufu, Oita 879-5593, Japan.ORCID 0000-0002-9289-478X
Hiroaki MiyaharaDepartment of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, Aichi 480-1195, Japan.
Masanori InoueDepartment of Pediatrics, Oita University Faculty of Medicine, Yufu, Oita 879-5593, Japan.
Kyoko KiyotaDepartment of Pediatrics, Oita University Faculty of Medicine, Yufu, Oita 879-5593, Japan.
Kumiko SakaiInstitute for Research Promotion, Oita University Faculty of Medicine, Yufu, Oita 879-5593, Japan.
Toshikatsu HanadaDepartment of Cell Biology, Oita University Faculty of Medicine, Yufu, Oita 879-5593, Japan.
Kenji IharaDepartment of Pediatrics, Oita University Faculty of Medicine, Yufu, Oita 879-5593, Japan.ORCID 0000-0002-8831-1991
Oita University · JPAichi Medical University · JP

Funding

Japan Society for the Promotion of Science 17K10182
6 · The paper itself

Abstract

The liver function is essential for metabolism, detoxification, and bile synthesis, even in the neonatal period. Autophagy plays significance roles in THE adult liver, whereas the role of liver autophagy in the early neonatal period largely remains unclear. To clarify the importance of liver autophagy in the neonatal starvation period, we generated liver-specific autophagy-deficient (

Indexed as

AutophagyMetabolomeAnimalsAnimals, NewbornAutophagy-Related Protein 5Gas Chromatography-Mass SpectrometryLiverMiceStarvationAutophagy-Related Protein 5autophagyinfantlivermetabolomestarvation

Identifiers

PMID34578904
PMCPMC8470362
OpenAlexW3198015758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.