Evidence map›Paper›PMID 34578888›Full record

ArticleNutrients2021

Stress Hyperglycemia and Osteocalcin in COVID-19 Critically Ill Patients on Artificial Nutrition.

Francisco Arrieta, Victoria Martinez-Vaello, Nuria Bengoa, Marta Rosillo, Angélica de Pablo, Cristina Voguel, Rosario Pintor, Amaya Belanger-Quintana, Raquel Mateo-Lobo, Angel Candela and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. The Role of Stress Hyperglycemia on Delirium Onset.Journal of clinical medicine · 2025
    Review
  6. Osteoporosis in Adrenal Insufficiency: Could Metformin be Protective?Indian journal of clinical biochemistry : IJCB · 2025
    Review
  7. Long-term implications of COVID-19 on bone health: pathophysiology and therapeutics.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Francisco ArrietaDepartment of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Victoria Martinez-VaelloDepartment of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Nuria BengoaDepartment of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Marta RosilloDepartment of Biochemistry, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0001-9279-5012
Angélica de PabloDepartment of Anesthesiology, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Cristina VoguelDepartment of Anesthesiology, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Rosario PintorDepartment of Pharmacy, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Amaya Belanger-QuintanaDepartment of Pediatrics, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Raquel Mateo-LoboDepartment of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Angel CandelaDepartment of Anesthesiology, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
José I Botella-CarreteroDepartment of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0002-6425-2747
Hospital Universitario Ramón y Cajal · ESCentro de Investigación Biomédica en Red · ES

Funding

This research was funded by Vegenat Healthcare 147/20
6 · The paper itself

Abstract

We aimed to study the possible association of stress hyperglycemia in COVID-19 critically ill patients with prognosis, artificial nutrition, circulating osteocalcin, and other serum markers of inflammation and compare them with non-COVID-19 patients. Fifty-two critical patients at the intensive care unit (ICU), 26 with COVID-19 and 26 non-COVID-19, were included. Glycemic control, delivery of artificial nutrition, serum osteocalcin, total and ICU stays, and mortality were recorded. Patients with COVID-19 had higher ICU stays, were on artificial nutrition for longer (

Indexed as

SARS-CoV-2AgedBiomarkersCOVID-19Critical Care OutcomesCritical IllnessFemaleHumansHyperglycemiaIntensive Care UnitsLength of StayMaleMiddle AgedOsteocalcinParenteral NutritionPrognosisBiomarkersOsteocalcinCOVID-19enteral nutritionhyperglycemiaosteocalcinparenteral nutrition

Identifiers

PMID34578888
PMCPMC8470880
OpenAlexW3198573410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.