Evidence map›Paper›PMID 34578863›Full record

Trial reportNutrients2021

Effect of Vitamin D-Enriched Gouda-Type Cheese Consumption on Biochemical Markers of Bone Metabolism in Postmenopausal Women in Greece.

George Moschonis, Ellen Ghm van den Heuvel, Christina Mavrogianni, Yannis Manios

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05346419 (Risedronate With High-dose Vitamin D Resolves Hyperparathyroidism and Hypovitaminosis D But Not Osteoporosis in Mexican Postmenopausal Patients), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05346419 nacompletednot on this map

Risedronate With High-dose Vitamin D Resolves Hyperparathyroidism and Hypovitaminosis D But Not Osteoporosis in Mexican Postmenopausal Patients

TypeinterventionalSponsorHospital Regional 1o de OctubreRan2021 to 2022Enrolled33ConditionsPostmenopausal Osteoporosis, Hypovitaminosis D, HyperparathyroidismArmsRisedronate, Vitamin D
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

George MoschonisDepartment of Dietetics, Nutrition and Sport, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne 3086, Australia.ORCID 0000-0003-3009-6675
Ellen Ghm van den HeuvelFrieslandCampina, Stationsplein 4, Post Box 1551, 3800 BN Amersfoort, The Netherlands.
Christina MavrogianniDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 17671 Athens, Greece.ORCID 0000-0002-3534-6832
Yannis ManiosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 17671 Athens, Greece.ORCID 0000-0001-6486-114X
Harokopio University of Athens · GRFrieslandCampina (Netherlands) · NLLa Trobe University · AU

Funding

Seventh Framework Programme 613977
6 · The paper itself

Abstract

Considering the role of bone metabolism in understanding the pathogenesis of osteoporosis, the aim of the present study was to examine the effects of vitamin D-enriched cheese on the serum concentrations of the parathyroid hormone (PTH) and certain bone remodeling biomarkers in postmenopausal women in Greece. In a randomised, controlled dietary intervention, 79 postmenopausal women (55-75 years old) were randomly allocated either to a control (CG: n = 39) or an intervention group (IG: n = 40), consuming 60 g of either non-enriched or vitamin D3-enriched Gouda-type cheese (5.7 μg of vitamin D3), respectively, daily and for eight weeks during the winter. The serum concentrations of 25-hydroxy vitamin D (25(OH)D), PTH, bone formation (i.e., osteocalcin, P1NP) and bone resorption (i.e., TRAP-5b) biomarkers were measured. Consumption of the vitamin D-enriched cheese led to higher serum 25(OH)D concentrations of 23.4 ± 6.39 (

Indexed as

CheeseFood, FortifiedAgedBiomarkersBone RemodelingBone ResorptionFemaleGreeceHumansMiddle AgedOsteocalcinOsteoporosis, PostmenopausalParathyroid HormonePostmenopauseSingle-Blind MethodSocioeconomic Factors25-hydroxyvitamin DBiomarkersOsteocalcinParathyroid HormoneVitamin DVitaminsbone remodelingcheeseenriched dairypostmenopausal womenvitamin D

Identifiers

PMID34578863
PMCPMC8470132
OpenAlexW3197952682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.