Evidence map›Paper›PMID 34578666›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Stretchable, Bio-Compatible, Antioxidant and Self-Powering Adhesives from Soluble Silk Fibroin and Vegetal Polyphenols Exfoliated Graphite.

Luca Valentini, Maria Rachele Ceccarini, Raquel Verdejo, Gianluca Tondi, Tommaso Beccari

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luca ValentiniCivil & Environmental Engineering Department, Università degli Studi di Perugia and INSTM Research Unit, Strada di Pentima 4, 05100 Terni, Italy.ORCID 0000-0002-6803-5889
Maria Rachele CeccariniDepartment of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.ORCID 0000-0002-5344-4890
Raquel VerdejoDepartment of Polymeric Nanomaterials and Biomaterials, Institute of Polymer Science and Technology, ICTP-CSIC, 28006 Madrid, Spain.ORCID 0000-0002-3049-0632
Gianluca TondiDepartment of Land Environment Agriculture and Forestry, University of Padua, 35020 Legnaro, Italy.ORCID 0000-0003-2383-6495
Tommaso BeccariDepartment of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.ORCID 0000-0001-9637-6579

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca 2017FWC3WC
6 · The paper itself

Abstract

The development of bio-glues is still a challenging task, regarding adhesion on wet surfaces; often, high performance and adaption to complex geometries need to be combined in one material. Here, we report biocompatible adhesives obtained by blending regenerated silk (RS) with a soluble plant-derived polyphenol (i.e., chestnut tannin) that was also used to exfoliate graphite to obtain graphene-based RS/tannin (G-RS/T) composites. The resultant G-RS/T hybrid material exhibited outstanding stretchability (i.e., 400%) and high shear strength (i.e., 180 kPa), superior to that of commercial bio-glues, and showed sealant properties for tissue approximation. Moreover, we showed how such nanocomposites exhibit electromechanical properties that could potentially be used for the realization of green and eco-friendly piezoelectric devices. Finally, we demonstrate the in vitro glue's biocompatibility and anti-oxidant properties that enable their utilization in clinical applications.

Indexed as

adhesionbiocompatibilityexfoliated graphitemechanical propertiesregenerated silktannin extracts

Identifiers

PMID34578666
PMCPMC8472279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.