ArticleNanomaterials (Basel, Switzerland)2021
Nano-Hydroxyapatite vs. Xenografts: Synthesis, Characterization, and In Vitro Behavior.
Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Nanohydroxyapatite and its composite scaffold for bone tissue engineering application: a systematic review.Journal of materials science. Materials in medicine · 2025Pooled it
- Comparative evaluation of porcine and bovine bone xenografts in bone grafting: a systematic review and meta-analysis.International journal of implant dentistry · 2025Pooled it
- The impact of deproteinized bovine bone particle size on histological outcomes in sinus floor elevation: a systematic review and meta-analysis.International journal of implant dentistry · 2023Pooled it
- A pilot study of the effect of two deproteinized bovine bone minerals in lateral window sinus floor elevation.BMC oral health · 2026Trial
- Nickel nanoparticles supported by fishbone-derived hydroxyapatite as a bifunctional catalyst for 4-nitrophenol reduction and methanation of carbon oxides.RSC advances · 2026Article
- Development and evaluation of a synthetic Cu-Zn-reinforced biphasic calcium phosphate scaffold for periodontal bone repair.Narra J · 2026Article
- Sustainable Synthesis and Dual-Function Sorption of Carbonated Hydroxyapatite for Cadmium and Nitrate Removal.International journal of molecular sciences · 2025Article
- Advances of Hydroxyapatite Nanoparticles in Dental Implant Applications.International dental journal · 2025Review
- A comprehensive analysis of two types of xenogeneic bone particles for use in maxillofacial bone regeneration therapies.PloS one · 2025Article
- Effect of Manipulation Methods and Storage Environments on the Microstructural, Chemical, and Mechanical Properties of Calcium-Enriched Mixture Cement.International journal of biomaterials · 2025Article
- Synthesis, Characterization, and Biological Performances of Magnesium-Substituted Dicalcium Phosphate Anhydrous.Materials (Basel, Switzerland) · 2024Article
- Comparing the effects of BoneClinical and experimental dental research · 2024Article
- Article
- Sustainable and Environmentally Friendly Microwave Synthesis of Nano-Hydroxyapatite from Decarbonized Eggshells.Materials (Basel, Switzerland) · 2024Article
- Comparison between Two Different Synthesis Methods of Strontium-Doped Hydroxyapatite Designed for Osteoporotic Bone Restoration.Materials (Basel, Switzerland) · 2024Article
- Synthesis of nano-hydroxyapatite using emulsion, pyrolysis, combustion, and sonochemical methods and biogenic sources: a review.RSC advances · 2024Review
- Comparison of the healing process of xenografts with three different sources in critical-size bone defects: An in vivo study.Journal of advanced periodontology & implant dentistry · 2024Article
- Investigation of the biological activity of hydroxyapatite on vascular endothelial cells.Heliyon · 2023Article
- Fabrication and Characterization of Porous Diopside/Akermanite Ceramics with Prospective Tissue Engineering Applications.Materials (Basel, Switzerland) · 2023Article
- Piezoelectric Biocomposites for Bone Grafting in Dentistry.Polymers · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
This research focused on the synthesis of apatite, starting from a natural biogenic calcium source (egg-shells) and its chemical and morpho-structural characterization in comparison with two commercial xenografts used as a bone substitute in dentistry. The synthesis route for the hydroxyapatite powder was the microwave-assisted hydrothermal technique, starting from annealed egg-shells as the precursor for lime and di-base ammonium phosphate as the phosphate precursor. The powders were characterized by Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray analysis (EDAX), transmission electron microscopy (TEM), X-ray fluorescence spectroscopy (XRF), and cytotoxicity assay in contact with amniotic fluid stem cell (AFSC) cultures. Compositional and structural similarities or differences between the powder synthesized from egg-shells (HA1) and the two commercial xenograft powders-Bio-Oss
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.