Evidence map›Paper›PMID 34578570›Full record

ReviewNanomaterials (Basel, Switzerland)2021

Non-Heating Alternating Magnetic Field Nanomechanical Stimulation of Biomolecule Structures via Magnetic Nanoparticles as the Basis for Future Low-Toxic Biomedical Applications.

Yuri I Golovin, Dmitry Yu Golovin, Ksenia Yu Vlasova, Maxim M Veselov, Azizbek D Usvaliev, Alexander V Kabanov, Natalia L Klyachko

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Frontiers in Nanotoxicology.Nanomaterials (Basel, Switzerland) · 2022
    Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuri I GolovinInstitute "Nanotechnology and Nanomaterials", G.R. Derzhavin Tambov State University, 392000 Tambov, Russia.
Dmitry Yu GolovinInstitute "Nanotechnology and Nanomaterials", G.R. Derzhavin Tambov State University, 392000 Tambov, Russia.
Ksenia Yu VlasovaDepartment of Chemical Enzymology, School of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.
Maxim M VeselovDepartment of Chemical Enzymology, School of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.
Azizbek D UsvalievDepartment of Chemical Enzymology, School of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.
Alexander V KabanovDepartment of Chemical Enzymology, School of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.
Natalia L KlyachkoInstitute "Nanotechnology and Nanomaterials", G.R. Derzhavin Tambov State University, 392000 Tambov, Russia.ORCID 0000-0002-9357-8236

Funding

Russian Foundation for Fundamental Investigations 18-29-09154
6 · The paper itself

Abstract

The review discusses the theoretical, experimental and toxicological aspects of the prospective biomedical application of functionalized magnetic nanoparticles (MNPs) activated by a low frequency non-heating alternating magnetic field (AMF). In this approach, known as nano-magnetomechanical activation (NMMA), the MNPs are used as mediators that localize and apply force to such target biomolecular structures as enzyme molecules, transport vesicles, cell organelles, etc., without significant heating. It is shown that NMMA can become a biophysical platform for a family of therapy methods including the addressed delivery and controlled release of therapeutic agents from transport nanomodules, as well as selective molecular nanoscale localized drugless nanomechanical impacts. It is characterized by low system biochemical and electromagnetic toxicity. A technique of 3D scanning of the NMMA region with the size of several mm to several cm over object internals has been described.

Indexed as

apoptosiscontrolled releaseimpact localizationmagnetic nanoparticlesnano-magneto-mechanical activationnon-heating low frequency magnetic fieldtoxicity

Identifiers

PMID34578570
PMCPMC8470408

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.