Evidence map›Paper›PMID 34578458›Full record

SynthesisViruses2021

Vertical Transmission of SARS-CoV-2: A Systematic Review of Systematic Reviews.

Salihu S Musa, Umar M Bello, Shi Zhao, Zainab U Abdullahi, Muhammad A Lawan, Daihai He

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. SARS-CoV-2 infection and female reproductive health: A narrative review.Best practice & research. Clinical endocrinology & metabolism · 2023
    Review
  9. Cross-Sectional Survey of Views on COVID-19 and Its Vaccines Among Pregnant Women.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2023
    Article
  10. Why the Silent Pandemic of Stillbirths Following COVID-19?Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. [Main changes in the «COVID-19 in paediatrics» clinical practice guideline].Anales de pediatria (Barcelona, Spain : 2003) · 2022
    Article
  18. Article
  19. Observational
  20. Severe Acute Respiratory Syndrome Coronavirus 2 and Blood Safety: An Updated Review.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Salihu S MusaDepartment of Applied Mathematics, Hong Kong Polytechnic University, Hong Kong, China.ORCID 0000-0001-6335-2335
Umar M BelloCentre for Eye and Vision Research (CEVR) Limited, Hong Kong Science Park, Hong Kong, China.ORCID 0000-0001-8535-4163
Shi ZhaoJC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0001-8722-6149
Zainab U AbdullahiDepartment of Biological Sciences, Federal University Dutsinma, Katsina 821101, Nigeria.ORCID 0000-0002-8753-7892
Muhammad A LawanDepartment of Mathematics, Kano University of Science and Technology, Wudil 713101, Nigeria.
Daihai HeDepartment of Applied Mathematics, Hong Kong Polytechnic University, Hong Kong, China.ORCID 0000-0003-3253-654X
Hong Kong Polytechnic University · HKChinese University of Hong Kong · HKFederal University Dutsin-MaKano State University of Technology · NGYobe State University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has hugely impacted global public health and economy. The COVID-19 has also shown potential impacts on maternal perinatal and neonatal outcomes. This systematic review aimed to summarize the evidence from existing systematic reviews about the effects of SARS-CoV-2 infections on maternal perinatal and neonatal outcomes. We searched PubMed, MEDLINE, Embase, and Web of Science in accordance with PRISMA guidelines, from 1 December 2019 to 7 July 2021, for published review studies that included case reports, primary studies, clinical practice guidelines, overviews, case-control studies, and observational studies. Systematic reviews that reported the plausibility of mother-to-child transmission of COVID-19 (also known as vertical transmission), maternal perinatal and neonatal outcomes, and review studies that addressed the effect of SARS-CoV-2 infection during pregnancy were also included. We identified 947 citations, of which 69 studies were included for further analysis. Most (>70%) of the mother-to-child infection was likely due to environmental exposure, although a significant proportion (about 20%) was attributable to potential vertical transmission of SARS-CoV-2. Further results of the review indicated that the mode of delivery of pregnant women infected with SARS-CoV-2 could not increase or decrease the risk of infection for the newborns (outcomes), thereby emphasizing the significance of breastfeeding. The issue of maternal perinatal and neonatal outcomes with SARS-CoV-2 infection continues to worsen during the ongoing COVID-19 pandemic, increasing maternal and neonatal mortality, stillbirth, ruptured ectopic pregnancies, and maternal depression. Based on this study, we observed increasing rates of cesarean delivery from mothers with SARS-CoV-2 infection. We also found that SARS-CoV-2 could be potentially transmitted vertically during the gestation period. However, more data are needed to further investigate and follow-up, especially with reports of newborns infected with SARS-CoV-2, in order to examine a possible long-term adverse effect.

Indexed as

COVID-19Infectious Disease Transmission, VerticalPregnancy Complications, InfectiousSARS-CoV-2Cesarean SectionFemaleHumansPregnancyPregnancy OutcomeSystematic Reviews as TopicCOVID-19pandemicpregnancysystematic reviewvertical transmission

Identifiers

PMID34578458
PMCPMC8471858
OpenAlexW3201388234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.