Evidence map›Paper›PMID 34578374›Full record

ArticleViruses2021

The Methanolic Extract of

Yu-Ting Kuo, Ching-Hsuan Liu, Angela Corona, Elisa Fanunza, Enzo Tramontano, Liang-Tzung Lin

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Yu-Ting KuoDepartment of Medical Imaging, Chi Mei Medical Center, Tainan 710, Taiwan.
Ching-Hsuan LiuDepartment of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0002-5074-1785
Angela CoronaDepartment of Life and Environmental Sciences, University of Cagliari, Monserrato, 09124 Cagliari, Italy.ORCID 0000-0002-6630-8636
Elisa FanunzaDepartment of Life and Environmental Sciences, University of Cagliari, Monserrato, 09124 Cagliari, Italy.ORCID 0000-0002-2044-8473
Enzo TramontanoDepartment of Life and Environmental Sciences, University of Cagliari, Monserrato, 09124 Cagliari, Italy.ORCID 0000-0002-4849-0980
Liang-Tzung LinDepartment of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0001-7374-7234
University of Cagliari · ITTaipei Medical University · TWChi Mei Medical Center · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ebola virus (EBOV), one of the most infectious human viruses and a leading cause of viral hemorrhagic fever, imposes a potential public health threat with several recent outbreaks. Despite the difficulties associated with working with this pathogen in biosafety level-4 containment, a protective vaccine and antiviral therapeutic were recently approved. However, the high mortality rate of EBOV infection underscores the necessity to continuously identify novel antiviral strategies to help expand the scope of prophylaxis/therapeutic management against future outbreaks. This includes identifying antiviral agents that target EBOV entry, which could improve the management of EBOV infection. Herein, using EBOV glycoprotein (GP)-pseudotyped particles, we screened a panel of natural medicinal extracts, and identified the methanolic extract of

Indexed as

Viral Envelope ProteinsAntiviral AgentsEbolavirusHEK293 CellsHumansMethanolPerilla frutescensPlant ExtractsVirus InternalizationAntiviral AgentsMethanolPlant ExtractsViral Envelope ProteinsEbola virusglycoproteinnatural productPerilla frutescensviral entry inhibition

Identifiers

PMID34578374
PMCPMC8473196
OpenAlexW3197011572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.