Evidence map›Paper›PMID 34578365›Full record

ReviewViruses2021

Rhinovirus Inhibitors: Including a New Target, the Viral RNA.

Antonio Real-Hohn, Dieter Blaas

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Targeting G-quadruplexes to achieve antiviral activity.Bioorganic & medicinal chemistry letters · 2023
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Antonio Real-HohnCenter for Medical Biochemistry, Vienna Biocenter, Max Perutz Laboratories, Medical University of Vienna, Dr. Bohr Gasse 9/3, A-1030 Vienna, Austria.ORCID 0000-0003-0334-2877
Dieter BlaasCenter for Medical Biochemistry, Vienna Biocenter, Max Perutz Laboratories, Medical University of Vienna, Dr. Bohr Gasse 9/3, A-1030 Vienna, Austria.ORCID 0000-0002-9612-3376
Max Perutz Labs · AT

Funding

Austrian Science Fund FWF P 27444Austrian Science Fund FWF P 31392
6 · The paper itself

Abstract

Rhinoviruses (RVs) are the main cause of recurrent infections with rather mild symptoms characteristic of the common cold. Nevertheless, RVs give rise to enormous numbers of absences from work and school and may become life-threatening in particular settings. Vaccination is jeopardised by the large number of serotypes eliciting only poorly cross-neutralising antibodies. Conversely, antivirals developed over the years failed FDA approval because of a low efficacy and/or side effects. RV species A, B, and C are now included in the fifteen species of the genus

Indexed as

AminoquinolinesAnimalsAntiviral AgentsCapsidCapsid ProteinsEnterovirusEnterovirus InfectionsGenome, ViralHumansPicolinic AcidsPoliovirusRhinovirusRNA, ViralViral Nonstructural ProteinsViral ProteinsAminoquinolinesAntiviral AgentsCapsid ProteinsPicolinic AcidspyridostatinRNA, ViralViral Nonstructural ProteinsViral Proteinsanti-viraldrug candidateenterovirusG-quadruplexinhibitionpicornaviruspyridostatinrhinovirusuncoatingviral RNA structure

Identifiers

PMID34578365
PMCPMC8473194
OpenAlexW3197334320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.