Evidence map›Paper›PMID 34578344›Full record

ArticleViruses2021

CP100356 Hydrochloride, a P-Glycoprotein Inhibitor, Inhibits Lassa Virus Entry: Implication of a Candidate Pan-Mammarenavirus Entry Inhibitor.

Toru Takenaga, Zihan Zhang, Yukiko Muramoto, Sarah Katharina Fehling, Ai Hirabayashi, Yuki Takamatsu, Junichi Kajikawa, Sho Miyamoto, Masahiro Nakano, Shuzo Urata and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Toru TakenagaLaboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Shogoin-Kawahara-cho 53, Sakyo-ku, Kyoto 606-8507, Japan.
Zihan ZhangLaboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Shogoin-Kawahara-cho 53, Sakyo-ku, Kyoto 606-8507, Japan.
Yukiko MuramotoLaboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Shogoin-Kawahara-cho 53, Sakyo-ku, Kyoto 606-8507, Japan.
Sarah Katharina FehlingInstitute of Virology, Phillips University Marburg, Hans-Meerwein-Strasse 2, 35043 Marburg, Germany.
Ai HirabayashiLaboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Shogoin-Kawahara-cho 53, Sakyo-ku, Kyoto 606-8507, Japan.
Yuki TakamatsuLaboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Shogoin-Kawahara-cho 53, Sakyo-ku, Kyoto 606-8507, Japan.
Junichi KajikawaLaboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Shogoin-Kawahara-cho 53, Sakyo-ku, Kyoto 606-8507, Japan.
Sho MiyamotoLaboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Shogoin-Kawahara-cho 53, Sakyo-ku, Kyoto 606-8507, Japan.ORCID 0000-0001-6541-1722
Masahiro NakanoLaboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Shogoin-Kawahara-cho 53, Sakyo-ku, Kyoto 606-8507, Japan.ORCID 0000-0003-4247-9008
Shuzo UrataNational Research Center for the Control and Prevention of Infectious Diseases (CCPID), Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.
Allison GrosethLaboratory for Arenavirus Biology, Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, 17493 Greifswald-Insel Riems, Germany.ORCID 0000-0001-9528-5130
Thomas StreckerInstitute of Virology, Phillips University Marburg, Hans-Meerwein-Strasse 2, 35043 Marburg, Germany.ORCID 0000-0002-7857-937X
Takeshi NodaLaboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Shogoin-Kawahara-cho 53, Sakyo-ku, Kyoto 606-8507, Japan.
Kyoto University · JPPhilipps University of Marburg · DEFriedrich-Loeffler-Institut · DENagasaki University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lassa virus (LASV)-a member of the family

Indexed as

AnimalsAntiviral AgentsArenaviridaeATP Binding Cassette Transporter, Subfamily B, Member 1Chlorocebus aethiopsHumansIsoquinolinesLassa FeverLassa virusLymphocytic choriomeningitis virusQuinazolinesReceptors, VirusVero CellsVesicular StomatitisViral Fusion Protein InhibitorsVirus InternalizationAntiviral AgentsATP Binding Cassette Transporter, Subfamily B, Member 1CP 100356IsoquinolinesQuinazolinesReceptors, VirusViral Fusion Protein Inhibitorsarenavirusentry inhibitorLassa viruslymphocytic choriomeningitis viruspseudotyped vesicular stomatitis virus

Identifiers

PMID34578344
PMCPMC8473031
OpenAlexW3197429436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.