Evidence map›Paper›PMID 34578242›Full record

ArticlePathogens (Basel, Switzerland)2021

Very High Fascioliasis Intensities in Schoolchildren from Nile Delta Governorates, Egypt: The Old World Highest Burdens Found in Lowlands.

M Victoria Periago, M Adela Valero, Patricio Artigas, Verónica H Agramunt, M Dolores Bargues, Filippo Curtale, Santiago Mas-Coma

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. The Clinical Picture Caused byOpen forum infectious diseases · 2025
    Article
  8. Article
  9. Fascioliasis.Advances in experimental medicine and biology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M Victoria PeriagoDepartamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andres Estelles s/n, 46100 Valencia, Spain.ORCID 0000-0002-1470-5146
M Adela ValeroDepartamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andres Estelles s/n, 46100 Valencia, Spain.ORCID 0000-0003-1584-8330
Patricio ArtigasDepartamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andres Estelles s/n, 46100 Valencia, Spain.ORCID 0000-0002-2815-1324
Verónica H AgramuntDepartamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andres Estelles s/n, 46100 Valencia, Spain.
M Dolores BarguesDepartamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andres Estelles s/n, 46100 Valencia, Spain.ORCID 0000-0003-2347-7269
Filippo CurtaleU.O.C. Rapporti internazionali, con le Regioni e Gestione del Ciclo di Progetto, Istituto Nazionale per la Promozione della Salute delle Popolazioni Migranti e il Contrasto delle Malattie della Povertà, 00153 Roma, Italy.
Santiago Mas-ComaDepartamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andres Estelles s/n, 46100 Valencia, Spain.ORCID 0000-0002-1685-7004

Funding

Agencia Española de Cooperación Internacional para el Desarrollo (A.E.C.I.D.) of the Spanish Ministry of Foreign Affairs (Madrid, Spain). P. Artigas predoctoral MAE fellowshipMinistry of Education . Madrid, Spain BOS2002-01978Ministry of Health and Population (MoHP), Egypt and the Directorate General for Cooperation and Development (DGCS), Ministry of Foreign Af-fairs, Italy AID No. 3703Ministry of Health, Madrid, Spain PI030545Ministry of Science and Technology, Madrid, Spain SAF2006-09278 and No. SAF2010-20805Programme of Redes Temáticas de Investigación Cooperativa RETICS/FEDER), FIS, Ministry of Health, Madrid, Spain C03/04, ISCIII2005-PI050574 and ISCIII-RETIC RD06/0021/0017
6 · The paper itself

Abstract

Quantitative coprological analyses of children were performed in Alexandria and Behera governorates, Egypt, to ascertain whether individual intensities in the Nile Delta lowlands reach high levels as those known in hyperendemic highland areas of Latin America. Analyses focused on subjects presenting intensities higher than 400 eggs per gram of faeces (epg), the high burden cut-off according to WHO classification. A total of 96 children were found to shed between 408 and 2304 epg, with arithmetic and geometric means of 699.5 and 629.07 epg, respectively. Intensities found are the highest hitherto recorded in Egypt, and also in the whole Old World. A total of 38 (39.6%) were males and 58 (60.4%) were females, with high intensities according to gender following a negative binomial distribution. The high burden distribution shows a peak in the 7-10 year-old children group, more precocious in females than males. Results showed high burdens in winter to be remarkably higher than those known in summer. The fascioliasis scenario in Egyptian lowlands shows similarities to highlands of Bolivia and Peru. Diagnostic methods, pathogenicity and morbidity in high burdens should be considered. The need for an appropriate quantitative assessment of heavy infected children to avoid post-treatment colic episodes is highlighted.

Indexed as

Alexandria and Behera governorateschildrencoprologyEgyptgender and agegeographical distributionhigh intensitieshuman fascioliasisNile Delta

Identifiers

PMID34578242
PMCPMC8470878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.