Evidence map›Paper›PMID 34578212›Full record

ArticlePathogens (Basel, Switzerland)2021

Intestinal Transcriptomic and Histologic Profiling Reveals Tissue Repair Mechanisms Underlying Resistance to the Parasite

Damien E Barrett, Itziar Estensoro, Ariadna Sitjà-Bobadilla, Jerri L Bartholomew

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. The Tilapia Cyst Tissue Enclosing the ProliferatingInternational journal of molecular sciences · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Parasitology · 2022
    Review
  10. Infection by the ParasiteMicroorganisms · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Damien E BarrettDepartment of Microbiology, Oregon State University, Corvallis, OR 97331-3804, USA.
Itziar EstensoroFish Pathology Group, Instituto de Acuicultura Torre de la Sal, Consejo Superior de Investigaciones Científicas, 12595 Castellón, Spain.ORCID 0000-0002-6218-2191
Ariadna Sitjà-BobadillaFish Pathology Group, Instituto de Acuicultura Torre de la Sal, Consejo Superior de Investigaciones Científicas, 12595 Castellón, Spain.ORCID 0000-0002-7473-3413
Jerri L BartholomewDepartment of Microbiology, Oregon State University, Corvallis, OR 97331-3804, USA.
Consejo Superior de Investigaciones Científicas · ESOregon State University · US

Funding

Bureau of Reclamation R19PG00027
6 · The paper itself

Abstract

backgroundMyxozoan parasites infect fish worldwide causing significant disease or death in many economically important fish species, including rainbow trout and steelhead trout (

resultsSequencing of intestinal mRNA from resistant steelhead trout with severe

conclusionsOur results suggest that resistance to ceratomyxosis involves both a rapid induction of key immune factors and a tissue response that limits the spread of the parasite and the subsequent tissue damage. These results improve our understanding of the myxozoan-host dialogue and provide a framework for future studies investigating the infection dynamics of

Indexed as

Ceratonova shastahost–parasite interactionimmune responsemyxozoanOncorhynchus mykissparasitesRNA-seqsteelheadtranscriptomics

Identifiers

PMID34578212
PMCPMC8467531
OpenAlexW3200643910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.