Evidence map›Paper›PMID 34578167›Full record

ArticlePathogens (Basel, Switzerland)2021

HERV-W and

Marta Noli, Gianfranco Meloni, Pietro Manca, Davide Cossu, Mario Palermo, Leonardo A Sechi

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Microorganisms · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Hermon-Taylor:Pathogens (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marta NoliDipartimento di Scienze Biomediche, Università degli Studi di Sassari, 07100 Sassari, Italy.ORCID 0000-0003-1087-4871
Gianfranco MeloniDipartimento di Medicina Mediche, Chirurgiche e Sperimentali, Università degli Studi di Sassari, 07100 Sassari, Italy.ORCID 0000-0002-0604-8924
Pietro MancaServizio Centro Trasfusionale, Azienda Ospedaliera Universitaria Sassari, 07100 Sassari, Italy.
Davide CossuDipartimento di Scienze Biomediche, Università degli Studi di Sassari, 07100 Sassari, Italy.ORCID 0000-0002-0557-9467
Mario PalermoServizio di Endocrinologia, Azienda Ospedaliera Universitaria Sassari, 07100 Sassari, Italy.
Leonardo A SechiDipartimento di Scienze Biomediche, Università degli Studi di Sassari, 07100 Sassari, Italy.ORCID 0000-0003-0566-2049
University of Sassari · ITAzienda Ospedaliero Universitaria di Sassari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The etiology of T1D remains unknown, although a variety of etiological agents have been proposed as potential candidates to trigger autoimmunity in susceptible individuals. Emerging evidence has indicated that endogenous human retrovirus (HERV) may play a role in the disease etiopathogenesis; although several epigenetic mechanisms keep most HERVs silenced, environmental stimuli such as infections may contribute to the transcriptional reactivation of HERV-Wand thus promote pathological conditions. Previous studies have indicated that also

Indexed as

antibodieschildren T1D onsetHERV-Wmolecular mimicryMycobacterium paratuberculosispeptidesproinsulin

Identifiers

PMID34578167
PMCPMC8471288
OpenAlexW3196789051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.