Evidence map›Paper›PMID 34578163›Full record

ArticlePathogens (Basel, Switzerland)2021

Comparison of Three Real-Time PCR Assays Targeting the SSU rRNA Gene, the COWP Gene and the DnaJ-Like Protein Gene for the Diagnosis of

Felix Weinreich, Andreas Hahn, Kirsten Alexandra Eberhardt, Torsten Feldt, Fred Stephen Sarfo, Veronica Di Cristanziano, Hagen Frickmann, Ulrike Loderstädt

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  5. Molecular detection ofOpen veterinary journal · 2024
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Felix WeinreichDepartment of Microbiology and Hospital Hygiene, Bundeswehr Hospital Hamburg, 20359 Hamburg, Germany.ORCID 0000-0001-9173-7072
Andreas HahnDepartment of Medical Microbiology, Virology and Hygiene, University Medicine Rostock, 18057 Rostock, Germany.ORCID 0000-0002-5157-8369
Kirsten Alexandra EberhardtInstitute of Transfusion Medicine, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.ORCID 0000-0002-1002-0326
Torsten FeldtDepartment of Gastroenterology, Hepatology and Infectious Diseases, University Medical Center Düsseldorf, 40225 Düsseldorf, Germany.
Fred Stephen SarfoDepartment of Medicine, Kwame Nkrumah University of Science and Technology, Kumasi 00233, Ghana.
Veronica Di CristanzianoInstitute of Virology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50935 Cologne, Germany.ORCID 0000-0003-1604-8386
Hagen FrickmannDepartment of Microbiology and Hospital Hygiene, Bundeswehr Hospital Hamburg, 20359 Hamburg, Germany.ORCID 0000-0002-8967-9528
Ulrike LoderstädtDepartment of Hospital Hygiene & Infectious Diseases, University Medicine Göttingen, 37075 Göttingen, Germany.
Bundeswehrkrankenhaus · DEDüsseldorf University Hospital · DEKwame Nkrumah University of Science and Technology · GHUniversität Hamburg · DEUniversitätsmedizin Göttingen · DEUniversity of Cologne · DE

Funding

Bundesministerium der Verteidigung 36K2-S-45 1922
6 · The paper itself

Abstract

As qualified microscopy of enteric parasitoses as defined by high diagnostic accuracy is difficult to maintain in non-endemic areas due to scarce opportunities for practicing with positive sample materials, molecular diagnostic options provide less investigator-dependent alternatives. Here, we compared three molecular targets for the real-time PCR-based detection of

Indexed as

Cryptosporidium spp.diagnostic accuracylatent class analysisreal-time PCRsensitivityspecificitytest comparison

Identifiers

PMID34578163
PMCPMC8472038
OpenAlexW3197605439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.