Evidence map›Paper›PMID 34578094›Full record

ArticlePolymers2021

Development of Novel Thin Polycaprolactone (PCL)/Clay Nanocomposite Films with Antimicrobial Activity Promoted by the Study of Mechanical, Thermal, and Surface Properties.

Sylva Holešová, Karla Čech Barabaszová, Marianna Hundáková, Michaela Ščuková, Kamila Hrabovská, Kamil Joszko, Magdalena Antonowicz, Bożena Gzik-Zroska

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Overview of Antimicrobial Biodegradable Polyester-Based Formulations.International journal of molecular sciences · 2023
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Sylva HolešováNanotechnology Centre, CEET, VŠB-Technical University of Ostrava, 17. Listopadu 2172/15, 708 00 Ostrava, Czech Republic.ORCID 0000-0001-5233-5847
Karla Čech BarabaszováNanotechnology Centre, CEET, VŠB-Technical University of Ostrava, 17. Listopadu 2172/15, 708 00 Ostrava, Czech Republic.ORCID 0000-0002-8667-4633
Marianna HundákováNanotechnology Centre, CEET, VŠB-Technical University of Ostrava, 17. Listopadu 2172/15, 708 00 Ostrava, Czech Republic.
Michaela ŠčukováNanotechnology Centre, CEET, VŠB-Technical University of Ostrava, 17. Listopadu 2172/15, 708 00 Ostrava, Czech Republic.
Kamila HrabovskáDepartment of Physics, Faculty of Electrical Engineering and Computer Science, VŠB-Technical University of Ostrava, 17. Listopadu 2172/15, 708 00 Ostrava, Czech Republic.ORCID 0000-0003-4563-6558
Kamil JoszkoDepartment of Biomechatronics, Faculty of Biomedical Engineering, Silesian University of Technology, Roosevelta 40, 41-800 Zabrze, Poland.ORCID 0000-0002-8229-3032
Magdalena AntonowiczDepartment of Biomaterials and Medical Devices Engineering, Faculty of Biomedical Engineering, Silesian University of Technology, Roosevelta 40, 41-800 Zabrze, Poland.ORCID 0000-0001-5755-490X
Bożena Gzik-ZroskaDepartment of Biomaterials and Medical Devices Engineering, Faculty of Biomedical Engineering, Silesian University of Technology, Roosevelta 40, 41-800 Zabrze, Poland.ORCID 0000-0003-4286-001X
VSB - Technical University of Ostrava · CZSilesian University of Technology · PL

Funding

Ministerstvo Školství, Mládeže a Tělovýchovy No. SP2020/08 - Hybrid clay nanofillers for antimicrobial polymer filmsMinisterstvo Školství, Mládeže a Tělovýchovy No. SP2021/106 - Study and development of composite nanomaterials and nanofillers
6 · The paper itself

Abstract

Infection with pathogenic microorganisms is of great concern in many areas, especially in healthcare, but also in food packaging and storage, or in water purification systems. Antimicrobial polymer nanocomposites have gained great popularity in these areas. Therefore, this study focused on new approaches to develop thin antimicrobial films based on biodegradable polycaprolactone (PCL) with clay mineral natural vermiculite as a carrier for antimicrobial compounds, where the active organic antimicrobial component is antifungal ciclopirox olamine (CPX). For possible synergistic effects, a sample in combination with the inorganic antimicrobial active ingredient zinc oxide was also prepared. The structures of all the prepared samples were studied by X-ray diffraction, FTIR analysis and, predominantly, by SEM. The very different structure properties of the prepared nanofillers had a fundamental influence on the final structural arrangement of thin PCL nanocomposite films as well as on their mechanical, thermal, and surface properties. As sample PCL/ZnOVER_CPX possessed the best results for antimicrobial activity against examined microbial strains, the synergic effect of CPX and ZnO combination on antimicrobial activity was proved, but on the other hand, its mechanical resistance was the lowest.

Indexed as

antimicrobial activitynanocompositespolycaprolactonethin filmsvermiculite

Identifiers

PMID34578094
PMCPMC8470023
OpenAlexW3201119484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.