Evidence map›Paper›PMID 34578039›Full record

ReviewPolymers2021

Evaluating the Anticarcinogenic Activity of Surface Modified/Functionalized Nanochitosan: The Emerging Trends and Endeavors.

Jae-Wook Oh, Juhyun Shin, Sechul Chun, Manikandan Muthu, Judy Gopal

Abstract readReview
In one paragraph

Review in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jae-Wook OhDepartment of Stem Cell and Regenerative Biotechnology, Konkuk University, Seoul 143-701, Korea.ORCID 0000-0003-2439-0499
Juhyun ShinDepartment of Stem Cell and Regenerative Biotechnology, Konkuk University, Seoul 143-701, Korea.
Sechul ChunDepartment of Environmental Health Science, Konkuk University, Seoul 143-701, Korea.ORCID 0000-0003-0845-9783
Manikandan MuthuDepartment of Environmental Health Science, Konkuk University, Seoul 143-701, Korea.
Judy GopalDepartment of Environmental Health Science, Konkuk University, Seoul 143-701, Korea.ORCID 0000-0003-0090-5160

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chitosan begins its humble journey from marine food shell wastes and ends up as a versatile nutraceutical. This review focuses on briefly discussing the antioxidant activity of chitosan and retrospecting the accomplishments of chitosan nanoparticles as an anticarcinogen. The various modified/functionalized/encapsulated chitosan nanoparticles and nanoforms have been listed and their biomedical deliverables presented. The anticancer accomplishments of chitosan and its modified composites have been reviewed and presented. The future of surface modified chitosan and the lacunae in the current research focus have been discussed as future perspective. This review puts forth the urge to expand the scientific curiosity towards attempting a variety of functionalization and surface modifications to chitosan. There are few well known modifications and functionalization that benefit biomedical applications that have been proven for other systems. Being a biodegradable, biocompatible polymer, chitosan-based nanomaterials are an attractive option for medical applications. Therefore, maximizing expansion of its bioactive properties are explored. The need for applying the ideal functionalization that will significantly promote the anticancer contributions of chitosan nanomaterials has also been stressed.

Indexed as

biomedical applicationschitosanfunctionalizationnanochitosansea food wastesurface modifications

Identifiers

PMID34578039
PMCPMC8471611

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.