Evidence map›Paper›PMID 34577877›Full record

ArticleMedicina (Kaunas, Lithuania)2021

Relation between Alpha-Synuclein and Core CSF Biomarkers of Alzheimer's Disease.

Victoria Monge-García, María-Salud García-Ayllón, Javier Sáez-Valero, José Sánchez-Payá, Francisco Navarrete-Rueda, Jorge Manzanares-Robles, Ruth Gasparini-Berenguer, Raquel Romero-Lorenzo, María Angeles Cortés-Gómez, José-Antonio Monge-Argilés

Open access · goldAbstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. A hypothesis explaining Alzheimer's disease, Parkinson's disease, and dementia with Lewy bodies overlap.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. α-synuclein-assisted oligomerization of β-amyloid (1-42).Archives of biochemistry and biophysics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Victoria Monge-GarcíaRehabilitation Service, University General Hospital of Alicante, 03010 Alicante, Spain.
María-Salud García-AyllónResearch Unit, University General Hospital of Elche, FISABIO, 03456 Elche, Spain.ORCID 0000-0001-5140-9752
Javier Sáez-ValeroResearch Unit, University General Hospital of Elche, FISABIO, 03456 Elche, Spain.
José Sánchez-PayáInstitute of Sanitary and Biomedical Research of Alicante (ISABIAL), 03010 Alicante, Spain.
Francisco Navarrete-RuedaInstituto de Neurociencias de Alicante, Miguel Hernández-CSIC, San Juan de Alicante, 03550 Alicante, Spain.
Jorge Manzanares-RoblesInstituto de Neurociencias de Alicante, Miguel Hernández-CSIC, San Juan de Alicante, 03550 Alicante, Spain.
Ruth Gasparini-BerenguerNeurology Department, University General Hospital of Alicante, 03010 Alicante, Spain.
Raquel Romero-LorenzoNeurology Department, University General Hospital of Alicante, 03010 Alicante, Spain.
María Angeles Cortés-GómezInstituto de Neurociencias de Alicante, Miguel Hernández-CSIC, San Juan de Alicante, 03550 Alicante, Spain.
José-Antonio Monge-ArgilésInstitute of Sanitary and Biomedical Research of Alicante (ISABIAL), 03010 Alicante, Spain.ORCID 0000-0002-8698-7699
Hospital General Universitario de Alicante Doctor Balmis · ESInstituto de Neurociencias · ESBiomedical Research Networking Center on Neurodegenerative Diseases · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseLewy Body Diseasealpha-SynucleinBiomarkersCross-Sectional StudiesHumansalpha-SynucleinBiomarkersSNCA protein, humanAlzheimer’sbiomarkerLewy body diseasemild cognitive impairmentα-synuclein

Identifiers

PMID34577877
PMCPMC8469325
OpenAlexW3199409295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.