Evidence map›Paper›PMID 34577840›Full record

ReviewMedicina (Kaunas, Lithuania)2021

Topical Wound Oxygen Therapy in the Treatment of Chronic Diabetic Foot Ulcers.

Robert G Frykberg

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05427760 (Effect of Using Oxygen on the Diaper Dermatitis in Infants), which is not on this map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05427760 nacompletednot on this mapstarted 2022, after this paper: background citation

Effect of Using Oxygen on the Diaper Dermatitis in Infants

TypeinterventionalSponsorIstanbul University - CerrahpasaRan2022 to 2023Enrolled103ConditionsDiaper Rash, Diaper DermatitisArmsOxygen
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
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  6. The Role of the Notch1 Signaling Pathway in the Pathogenesis and Treatment of Diabetic Foot: A Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Review
  7. Innovative wound management of refractory venous ulcers with topical oxygen therapy.Journal of vascular surgery. Venous and lymphatic disorders · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Robert G FrykbergDiabetic Foot Consultants, LLC, Midwestern University, Glendale, AZ 85308, USA.
Midwestern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxygen is a critical component of many biological processes and is essential for wound healing. Chronic wounds are typically characterized as being hypoxic in that the partial pressure of oxygen (pO

Indexed as

Diabetes MellitusDiabetic FootHyperbaric OxygenationAdministration, TopicalHumansOxygenWound HealingOxygendiabetic foot ulcersoxygentopical oxygen therapywound healing

Identifiers

PMID34577840
PMCPMC8467973
OpenAlexW3197540813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.