Evidence map›Paper›PMID 34577570›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Naproxen Based 1,3,4-Oxadiazole Derivatives as EGFR Inhibitors: Design, Synthesis, Anticancer, and Computational Studies.

Mohammad Mahboob Alam, Syed Nazreen, Abdulraheem S A Almalki, Ahmed A Elhenawy, Nawaf I Alsenani, Serag Eldin I Elbehairi, Azizah M Malebari, Mohammad Y Alfaifi, Meshari A Alsharif, Sulaiman Y M Alfaifi

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
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  8. Bioactivity and molecular docking of lactones isolated fromSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
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  12. Synthesis of 9-Hydroxy-1International journal of molecular sciences · 2022
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Monoterpene Indole Alkaloids from the Aerial Parts ofMolecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Mohammad Mahboob AlamDepartment of Chemistry, Faculty of Science, Albaha University, Albaha 65731, Saudi Arabia.
Syed NazreenDepartment of Chemistry, Faculty of Science, Albaha University, Albaha 65731, Saudi Arabia.ORCID 0000-0002-5093-1538
Abdulraheem S A AlmalkiDepartment of Chemistry, Faculty of Science, Taif University, Taif 21974, Saudi Arabia.ORCID 0000-0002-6463-4163
Ahmed A ElhenawyDepartment of Chemistry, Faculty of Science, Albaha University, Albaha 65731, Saudi Arabia.ORCID 0000-0003-2893-0376
Nawaf I AlsenaniDepartment of Chemistry, Faculty of Science, Albaha University, Albaha 65731, Saudi Arabia.
Serag Eldin I ElbehairiDepartment of Biology, Faculty of Science, King Khalid University, Abha 9004, Saudi Arabia.ORCID 0000-0003-4680-3215
Azizah M MalebariDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Mohammad Y AlfaifiDepartment of Biology, Faculty of Science, King Khalid University, Abha 9004, Saudi Arabia.ORCID 0000-0003-4310-3539
Meshari A AlsharifChemistry Department, Faculty of Applied Sciences, Umm Al-Qura University, Makkah 21421, Saudi Arabia.
Sulaiman Y M AlfaifiChemistry Department, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Al Baha University · SAKing Abdulaziz University · SAKing Khalid University · SAAl-Azhar University · EGTaif University · SAUmm al-Qura University · SA

Funding

Taif University TURSP-2020/44
6 · The paper itself

Abstract

A library of novel naproxen based 1,3,4-oxadiazole derivatives (

Indexed as

1,3,4-oxadiazolecomputational studycytotoxicityEGFRnaproxen

Identifiers

PMID34577570
PMCPMC8469912
OpenAlexW3197468369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.