Evidence map›Paper›PMID 34577543›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Utility of suPAR and NGAL for AKI Risk Stratification and Early Optimization of Renal Risk Medications among Older Patients in the Emergency Department.

Anne Byriel Walls, Anne Kathrine Bengaard, Esben Iversen, Camilla Ngoc Nguyen, Thomas Kallemose, Helle Gybel Juul-Larsen, Baker Nawfal Jawad, Mads Hornum, Ove Andersen, Jesper Eugen-Olsen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. suPAR: An Inflammatory Mediator for Kidneys.Kidney diseases (Basel, Switzerland) · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Anne Byriel WallsDepartment of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark.
Anne Kathrine BengaardDepartment of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark.
Esben IversenDepartment of Clinical Research, Copenhagen University Hospital-Amager and Hvidovre, 2650 Copenhagen, Denmark.
Camilla Ngoc NguyenDepartment of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark.
Thomas KallemoseDepartment of Clinical Research, Copenhagen University Hospital-Amager and Hvidovre, 2650 Copenhagen, Denmark.
Helle Gybel Juul-LarsenDepartment of Clinical Research, Copenhagen University Hospital-Amager and Hvidovre, 2650 Copenhagen, Denmark.
Baker Nawfal JawadDepartment of Clinical Research, Copenhagen University Hospital-Amager and Hvidovre, 2650 Copenhagen, Denmark.
Mads HornumDepartment of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.
Ove AndersenDepartment of Clinical Research, Copenhagen University Hospital-Amager and Hvidovre, 2650 Copenhagen, Denmark.
Jesper Eugen-OlsenDepartment of Clinical Research, Copenhagen University Hospital-Amager and Hvidovre, 2650 Copenhagen, Denmark.ORCID 0000-0002-4630-4275
Morten Baltzer HoulindDepartment of Drug Design and Pharmacology, University of Copenhagen, 2100 Copenhagen, Denmark.ORCID 0000-0003-4058-3012
University of Copenhagen · DKAmager Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosis of acute kidney injury (AKI) based on plasma creatinine often lags behind actual changes in renal function. Here, we investigated early detection of AKI using the plasma soluble urokinase plasminogen activator receptor (suPAR) and neutrophil gelatinase-sssociated lipocalin (NGAL) and observed the impact of early detection on prescribing recommendations for renally-eliminated medications. This study is a secondary analysis of data from the DISABLMENT cohort on acutely admitted older (≥65 years) medical patients (

Indexed as

acute kidney injuryearly biomarkeremergency departmentmedication optimizationolder patientsplasma neutrophil gelatinase-associated lipocalinsoluble urokinase plasminogen activator receptor

Identifiers

PMID34577543
PMCPMC8471084
OpenAlexW3198317209

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.