Evidence map›Paper›PMID 34577538›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Synthesis and Study of Antifungal Properties of New Cationic Beta-Glucan Derivatives.

Kamil Kaminski, Magdalena Skora, Paweł Krzyściak, Sylwia Stączek, Agnieszka Zdybicka-Barabas, Małgorzata Cytryńska

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kamil KaminskiFaculty of Chemistry, Jagiellonian University, Gronostajowa 2 St., 30-387 Krakow, Poland.ORCID 0000-0002-7421-6758
Magdalena SkoraDepartment of Infections Control and Mycology, Chair of Microbiology, Jagiellonian University Medical College, Czysta 18 St., 31-121 Krakow, Poland.
Paweł KrzyściakDepartment of Infections Control and Mycology, Chair of Microbiology, Jagiellonian University Medical College, Czysta 18 St., 31-121 Krakow, Poland.ORCID 0000-0002-2554-9409
Sylwia StączekDepartment of Immunobiology, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Sklodowska University, Akademicka 19 St., 20-033 Lublin, Poland.ORCID 0000-0002-4879-1329
Agnieszka Zdybicka-BarabasDepartment of Immunobiology, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Sklodowska University, Akademicka 19 St., 20-033 Lublin, Poland.ORCID 0000-0003-3146-3836
Małgorzata CytryńskaDepartment of Immunobiology, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Sklodowska University, Akademicka 19 St., 20-033 Lublin, Poland.ORCID 0000-0002-7621-2363
Jagiellonian University · PLMaria Curie-Skłodowska University · PL

Funding

Centre for Technology Transfer CITTRU Jagiellonian University N41/DBS/000591Institute of Biological Sciences (UMCS, Lublin, Poland) MN/2021/2
6 · The paper itself

Abstract

The interaction of positively charged polymers (polycations) with a biological membrane is considered to be the cause of the frequently observed toxicity of these macromolecules. If it is possible to obtain polymers with a predominantly negative effect on bacterial and fungal cells, such systems would have great potential in the treatment of infectious diseases, especially now when reports indicate the growing risk of fungal co-infections in COVID-19 patients. We describe in this article cationic derivatives of natural beta-glucan polymers obtained by reacting the polysaccharide isolated from

Indexed as

antifungalbeta-glucanGalleria mellonella modelpolycations

Identifiers

PMID34577538
PMCPMC8469811
OpenAlexW3194643810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.