Evidence map›Paper›PMID 34577195›Full record

ArticleMolecules (Basel, Switzerland)2021

Therapeutic Efficacy of Sesquiterpene Farnesol in Treatment of

Guan-Xuan Wu, Yu-Wen Wang, Chun-Shien Wu, Yen-Hung Lin, Chih-Hsin Hung, Han-Hsiang Huang, Shyh-Ming Kuo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Phytochemicals, promising strategies combatingFrontiers in pharmacology · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Guan-Xuan WuDepartment of Biomedical Engineering, I-Shou University, Kaohsiung City 82445, Taiwan.
Yu-Wen WangDepartment of Biomedical Engineering, I-Shou University, Kaohsiung City 82445, Taiwan.
Chun-Shien WuCenter of General Education, I-Shou University, Kaohsiung City 82445, Taiwan.
Yen-Hung LinInstitute of Biotechnology and Chemical Engineering, I-Shou University, Kaohsiung City 82445, Taiwan.
Chih-Hsin HungInstitute of Biotechnology and Chemical Engineering, I-Shou University, Kaohsiung City 82445, Taiwan.
Han-Hsiang HuangDepartment of Veterinary Medicine, National Chiayi University, Chiayi City 60054, Taiwan.
Shyh-Ming KuoDepartment of Biomedical Engineering, I-Shou University, Kaohsiung City 82445, Taiwan.
I-Shou University · TWNational Chiayi University · TWTajen University · TW

Funding

Ministry of Science and Technology, Taiwan 109-2622-E-214-001-CC2
6 · The paper itself

Abstract

Acne vulgaris is a highly prevalent skin disorder requiring treatment and management by dermatologists. Antibiotics such as clindamycin are commonly used to treat acne vulgaris. However, from both medical and public health perspectives, the development of alternative remedies has become essential due to the increase in antibiotic resistance. Topical therapy is useful as a single or combined treatment for mild and moderate acne and is often employed as maintenance therapy. Thus, the current study investigated the anti-inflammatory, antibacterial, and restorative effects of sesquiterpene farnesol on acne vulgaris induced by

Indexed as

Administration, CutaneousAnimalsAnti-Bacterial AgentsFarnesolHaCaT CellsHumansHypromellose DerivativesInterleukinsMaleMicrobial Sensitivity TestsPropionibacterium acnesRatsRats, Sprague-DawleySesquiterpenesSkin DiseasesTumor Necrosis Factor-alphaAnti-Bacterial AgentsFarnesolHypromellose DerivativesInterleukinsSesquiterpenesTumor Necrosis Factor-alphaantibacterialanti-inflammatoryclindamycinCutibacterium acnesfarnesol

Identifiers

PMID34577195
PMCPMC8465053
OpenAlexW3199266604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.