Evidence map›Paper›PMID 34577183›Full record

ReviewMolecules (Basel, Switzerland)2021

Antimalarial Inhibitors Targeting Epigenetics or Mitochondria in

Christina L Koumpoura, Anne Robert, Constantinos M Athanassopoulos, Michel Baltas

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christina L KoumpouraCNRS, LCC (Laboratoire de Chimie de Coordination), Université de Toulouse, UPS, INPT, Inserm ERL 1289, 205 Route de Narbonne, BP 44099, CEDEX 4, F-31077 Toulouse, France.ORCID 0000-0001-6819-7266
Anne RobertCNRS, LCC (Laboratoire de Chimie de Coordination), Université de Toulouse, UPS, INPT, Inserm ERL 1289, 205 Route de Narbonne, BP 44099, CEDEX 4, F-31077 Toulouse, France.ORCID 0000-0002-9092-6776
Constantinos M AthanassopoulosSynthetic Organic Chemistry Laboratory, Department of Chemistry, University of Patras, GR-26504 Patras, Greece.ORCID 0000-0002-7549-1911
Michel BaltasCNRS, LCC (Laboratoire de Chimie de Coordination), Université de Toulouse, UPS, INPT, Inserm ERL 1289, 205 Route de Narbonne, BP 44099, CEDEX 4, F-31077 Toulouse, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite many efforts, malaria remains among the most problematic infectious diseases worldwide, mainly due to the development of drug resistance by

Indexed as

AnimalsAntimalarialsDihydroorotate DehydrogenaseDNADrug DiscoveryDrug ResistanceEnzyme InhibitorsEpigenesis, GeneticHistone DeacetylasesHumansMalaria, FalciparumMethyltransferasesMitochondriaOxidoreductases Acting on CH-CH Group DonorsPlasmodium falciparumQuinazolinesAntimalarialsDihydroorotate DehydrogenaseDNAEnzyme InhibitorsHistone DeacetylasesMethyltransferasesOxidoreductases Acting on CH-CH Group DonorsQuinazolinesactivitiesdrug candidatesepigeneticmalariamitochondriasynthesis

Identifiers

PMID34577183
PMCPMC8467436

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.