Evidence map›Paper›PMID 34577157›Full record

ArticleMolecules (Basel, Switzerland)2021

Design, Synthesis, Antibacterial, and Antitumor Activity of Linear Polyisocyanide Quaternary Ammonium Salts with Different Structures and Chain Lengths.

Hongguang Zhang, Lijia Liu, Peng Hou, Jun Liu, Shuang Fu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hongguang ZhangCollege of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.ORCID 0000-0001-9247-9968
Lijia LiuKey Laboratory of Superlight Materials & Surface Technology, Ministry of Education, Institute of Advanced Marine Materials, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, China.ORCID 0000-0002-2181-747X
Peng HouCollege of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Jun LiuCollege of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.
Shuang FuCollege of Pharmacy, Qiqihar Medical University, Qiqihar 161006, China.

Funding

Science and Technology Research Project of Heilongjiang Provincial Education Department 2020-KYYWF-0021
6 · The paper itself

Abstract

The development of organic polymer materials for disinfection and sterilization is thought of as one of the most promising avenues to solve the growth and spread of harmful microorganisms. Here, a series of linear polyisocyanide quaternary ammonium salts (L-PQASs) with different structures and chain lengths were designed and synthesized by polymerization of phenyl isocyanide monomer containing a 4-chloro-1-butyl side chain followed by quaternary amination salinization. The resultant compounds were characterized by

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsCell Line, TumorEscherichia coliHumansIsocyanatesMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsPolymerizationPolyurethanesQuaternary Ammonium CompoundsSolubilitySpectroscopy, Fourier Transform InfraredStaphylococcus aureusStomach NeoplasmsStructure-Activity RelationshipAnti-Bacterial AgentsAntineoplastic AgentsIsocyanatesphenyl isocyanatePolyurethanesQuaternary Ammonium Compoundsantibacterialantitumorcontrolled polymerizationpolyisocyanidequaternary ammonium salt

Identifiers

PMID34577157
PMCPMC8472106

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.