Evidence map›Paper›PMID 34577081›Full record

ArticleMolecules (Basel, Switzerland)2021

Adulteration of Essential Oils: A Multitask Issue for Quality Control. Three Case Studies:

Francesca Capetti, Arianna Marengo, Cecilia Cagliero, Erica Liberto, Carlo Bicchi, Patrizia Rubiolo, Barbara Sgorbini

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. AdjunctiveFrontiers in pharmacology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Current Trends for Lavender (Plants (Basel, Switzerland) · 2023
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francesca CapettiDipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Via Pietro Giuria 9, I-10125 Turin, Italy.ORCID 0000-0002-1024-7088
Arianna MarengoDipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Via Pietro Giuria 9, I-10125 Turin, Italy.
Cecilia CaglieroDipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Via Pietro Giuria 9, I-10125 Turin, Italy.ORCID 0000-0003-3512-6124
Erica LibertoDipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Via Pietro Giuria 9, I-10125 Turin, Italy.ORCID 0000-0001-6675-8517
Carlo BicchiDipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Via Pietro Giuria 9, I-10125 Turin, Italy.ORCID 0000-0003-1782-7357
Patrizia RubioloDipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Via Pietro Giuria 9, I-10125 Turin, Italy.ORCID 0000-0002-6819-2614
Barbara SgorbiniDipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Via Pietro Giuria 9, I-10125 Turin, Italy.ORCID 0000-0001-6848-1304

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The quality control of essential oils (EO) principally aims at revealing the presence of adulterations and at quantifying compounds that are limited by law by evaluating EO chemical compositions, usually in terms of the normalised relative abundance of selected markers, for comparison to reference values reported in pharmacopoeias and/or international norms. Common adulterations of EO consist of the addition of cheaper EO or synthetic materials. This adulteration can be detected by calculating the percent normalised areas of selected markers or the enantiomeric composition of chiral components. The dilution of the EO with vegetable oils is another type of adulteration. This adulteration is quite devious, as it modifies neither the qualitative composition of the resulting EO nor the marker's normalised percentage abundance, which is no longer diagnostic, and an absolute quantitative analysis is required. This study aims at verifying the application of the two above approaches (i.e., normalised relative abundance and absolute quantitation) to detect EO adulterations, with examples involving selected commercial EO (lavender, bergamot and tea tree) adulterated with synthetic components, EO of different origin and lower economical values and heavy vegetable oils. The results show that absolute quantitation is necessary to highlight adulteration with heavy vegetable oils, providing that a reference quantitative profile is available.

Indexed as

Quality ControlAcyclic MonoterpenesCitrusDrug ContaminationGas Chromatography-Mass SpectrometryIsomerismLavandulaMelaleucaMonoterpenesOils, VolatilePlant OilsReference StandardsTea Tree OilAcyclic Monoterpenesbergamot oillavender oillinaloollinalyl acetateMonoterpenesOils, VolatilePlant OilsTea Tree Oiladulteration of essential oilschiral analysisCitrus limon (ex. Citrus × bergamia)Lavandula angustifoliaMelaleuca alternifolia

Identifiers

PMID34577081
PMCPMC8471154

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.