ReviewMolecules (Basel, Switzerland)2021
Wine, Polyphenols, and Mediterranean Diets. What Else Is There to Say?
Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Network meta-analysis of the effects of different dietary patterns on patients with metabolic syndrome.Frontiers in nutrition · 2025Pooled it
- Relevance of Mediterranean diet as a nutritional strategy in diminishing COVID-19 risk: A systematic review.PloS one · 2024Pooled it
- White Wine Intake Reduces Mitochondrial Complex I-Derived ROS in the Male Rat Heart.Antioxidants (Basel, Switzerland) · 2026Article
- Diabetic kidney disease: emerging mechanistic and nutritional perspectives from the Mediterranean diet-mitochondria axis. A narrative review.The journal of nutrition, health & aging · 2026Review
- A Short Questionnaire for Evaluating Mediterranean Diet Adherence and Nutritional Sustainability: Validation in Turkish Adults.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026Article
- Development of the Asian Mediterranean Diet and its sensory acceptability in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).BMC nutrition · 2026Article
- Bioaccessibility of anthocyanins and bioactive compounds from Brazilian berries and their food matrix interaction: an in vitro gastrointestinal digestion study coupled to UHPLC-ESI-TQD-MS/MS analysis.Journal of the science of food and agriculture · 2026Article
- Antioxidant Capacity and Polyphenolic Profile of Extractable and Non-Extractable Fractions of Traditional Mediterranean Diet Recipes from Different Regions.Antioxidants (Basel, Switzerland) · 2026Article
- Unveiling the antioxidant and anticancer potential of local mediterranean olive and fig extracts against breast cancer.BMC complementary medicine and therapies · 2026Article
- Regional dietary patterns and their impact on maternal, placental, and fetal fatty acid profiles during pregnancy: a multicenter study from Croatia.Frontiers in nutrition · 2026Article
- Beyond ethanol: wine, biological aging, and the Mediterranean context.International journal of public health · 2026Article
- Article
- A Narrative Review on the Antitumoral Effects of Selected Mediterranean Plant Products from Southern Italy.International journal of molecular sciences · 2025Review
- Modifiable Dietary Habits, Inflammatory Mediation, and Senile Cataract: Unraveling Causality via Mendelian Randomization.Food science & nutrition · 2025Article
- Article
- Gestational Diabetes Mellitus: Efficacy of Non-Pharmacological Interventions for Management and Prevention.Healthcare (Basel, Switzerland) · 2025Review
- Western Diet and Cognitive Decline: A Hungarian Perspective-Implications for the Design of the Semmelweis Study.Nutrients · 2025Review
- Regulation of Matrix Metalloproteinases by Wine-Derived Compounds: Implications for Cancer Therapy.Biomolecules · 2025Review
- Alcohol or No Alcohol in Wine: Half a Century of Debate.Foods (Basel, Switzerland) · 2025Review
- Excessive alcohol consumption: a driver of metabolic dysfunction and inflammation.Frontiers in toxicology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
A considerable amount of literature has been published claiming the cardiovascular benefits of moderate (red) wine drinking, which has been considered a distinguishing trait of the Mediterranean diet. Indeed, red wine contains relevant amounts of polyphenols, for which evidence of their biological activity and positive health effects are abundant; however, it is also well-known that alcohol, even at a low level of intake, may have severe consequences for health. Among others, it is directly related to a number of non-communicable diseases, like liver cirrhosis or diverse types of cancer. The IARC classifies alcohol as a Group 1 carcinogen, causally associated with the development of cancers of the upper digestive tract and liver, and, with sufficient evidence, can be positively associated with colorectum and female breast cancer. In these circumstances, it is tricky, if not irresponsible, to spread any message on the benefits of moderate wine drinking, about which no actual consensus exists. It should be further considered that other hallmarks of the Mediterranean diet are the richness in virgin olive oil, fruits, grains, and vegetables, which are also good sources of polyphenols and other phytochemicals, and lack the risks of wine. All of these aspects are reviewed in this article.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.