Evidence map›Paper›PMID 34577000›Full record

ArticleMolecules (Basel, Switzerland)2021

A Novel Approach to Unraveling the Apoptotic Potential of Rutin (Bioflavonoid) via Targeting

Pratibha Pandey, Fahad Khan, Faisal Abdulrahman Alzahrani, Huda A Qari, Mohammad Oves

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Potent Therapeutic Insights FromFood science & nutrition · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Pratibha PandeyDepartment of Biotechnology, Noida Institute of Engineering and Technology, Greater Noida 201306, India.ORCID 0000-0001-7029-8517
Fahad KhanDepartment of Biotechnology, Noida Institute of Engineering and Technology, Greater Noida 201306, India.ORCID 0000-0003-3449-7978
Faisal Abdulrahman AlzahraniDepartment of Biochemistry, Faculty of Science, Embryonic Stem Cells Unit, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0003-0441-4000
Huda A QariDepartment of biological Science, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Mohammad OvesCenter of Excellence in Environmental Studies, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-8513-6155
King Abdulaziz University · SAJaypee Institute of Information Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rutin has been well recognized for possessing numerous pharmacological and biological activities in several human cancer cells. This research has addressed the inhibitory potential of rutin against the

Indexed as

Apoptosisbcl-2-Associated X ProteinCaspase 3Caspase 9Cell Line, TumorCell SurvivalCOP9 Signalosome ComplexDown-RegulationFemaleHumansIntracellular Signaling Peptides and ProteinsMembrane Potential, MitochondrialPeptide HydrolasesProliferating Cell Nuclear AntigenProto-Oncogene Proteins c-bcl-2Reactive Oxygen SpeciesBAX protein, humanbcl-2-Associated X ProteinBCL2 protein, humanCASP3 protein, humanCASP9 protein, humanCaspase 3Caspase 9COP9 Signalosome ComplexCOPS5 protein, humanIntracellular Signaling Peptides and Proteinsp27 antigenPeptide HydrolasesProliferating Cell Nuclear AntigenProto-Oncogene Proteins c-bcl-2Reactive Oxygen SpeciesRutinTP53 protein, humanTumor Suppressor Protein p53apoptosisCaspase-3cervical cancerJab1oncogeneROSrutin

Identifiers

PMID34577000
PMCPMC8472561
OpenAlexW3200361351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.