Evidence map›Paper›PMID 34576886›Full record

ArticleMicroorganisms2021

Chagas Disease-Related Mortality in Spain, 1997 to 2018.

Jose-Manuel Ramos-Rincon, Jara Llenas-García, Hector Pinargote-Celorio, Veronica Sánchez-García, Philip Wikman-Jorgensen, Miriam Navarro, Concepción Gil-Anguita, Violeta Ramos-Sesma, Diego Torrus-Tendero

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Hospitalizations in adolescents with autism spectrum disorder are rising in Spain.Child and adolescent psychiatry and mental health · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Frontiers in cell and developmental biology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jose-Manuel Ramos-RinconInternal Medicine Department, Alicante Institute of Sanitary and Biomedical Research (ISABIAL), Alicante General University Hospital, 03010 Alicante, Spain.ORCID 0000-0002-6501-9867
Jara Llenas-GarcíaInternal Medicine Department, Hospital Vega Baja, Foundation for the Promotion of Health and Biomedical Research of the Valencia Region (FISABIO), 03314 Alicante, Spain.ORCID 0000-0001-9125-7706
Hector Pinargote-CelorioInternal Medicine Department, Alicante Institute of Sanitary and Biomedical Research (ISABIAL), Alicante General University Hospital, 03010 Alicante, Spain.ORCID 0000-0002-3300-5807
Veronica Sánchez-GarcíaDermatology Service, Alicante Institute of Sanitary and Biomedical Research (ISABIAL), Alicante General University Hospital, 03010 Alicante, Spain.ORCID 0000-0001-6680-9716
Philip Wikman-JorgensenInternal Medicine Department, Foundation for the Promotion of Health and Biomedical Research of the Valencia Region (FISABIO), University Hospital of Sant Joan, 03550 Alicante, Spain.ORCID 0000-0002-6329-0311
Miriam NavarroEpidemiology Unit, Public Health Center of Elche, 03302 Alicante, Spain.ORCID 0000-0001-7727-1587
Concepción Gil-AnguitaInternal Medicine Department, Hospital Marina Baixa-Foundation for the Promotion of Health and Biomedical Research of the Valencia Region (FISABIO), 03570 Alicante, Spain.
Violeta Ramos-SesmaInternal Medicine Service, HLA Inmaculada Hospital, 18004 Granada, Spain.ORCID 0000-0003-3976-6700
Diego Torrus-TenderoInfectious Diseases Unit, Alicante Institute of Sanitary and Biomedical Research (ISABIAL), Alicante General University Hospital, 03010 Alicante, Spain.
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana · ESUniversitat de Miguel Hernández d'Elx · ESHospital General Universitario de Alicante Doctor Balmis · ESHospital La Inmaculada · ES

Funding

Institute of Health and Biomedical Research of Alicante 190295Institute of Health and Biomedical Research of Alicante 2020-0285)
6 · The paper itself

Abstract

backgroundChagas disease (CD) is associated with excess mortality in infected people in endemic countries, but little information is available in non-endemic countries. The aim of the study was to analyze mortality in patients admitted to the hospital with CD in Spain.

methodsA retrospective, observational study using the Spanish National Hospital Discharge Database. We used the CD diagnostic codes of the 9th and 10th International Classification of Diseases to retrieve CD cases from the national public registry from 1997 to 2018.

resultsOf the 5022 hospital admissions in people with CD, there were 56 deaths (case fatality rate (CFR) 1.1%, 95% confidence interval (CI) 0.8%, 1.4%), 20 (35.7%) of which were considered directly related to CD. The median age was higher in those who died (54.5 vs. 38 years;

conclusionsThe case fatality rate of CD hospitalization was about 1%. The mortality risk increased with age, male sex, cancer, and HIV infection.

Indexed as

agedcardiopathyChagas diseasefemaleHIV infectionmalemortalityneoplasmSpain

Identifiers

PMID34576886
PMCPMC8469044
OpenAlexW3200909500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.