Evidence map›Paper›PMID 34576799›Full record

ArticleMicroorganisms2021

Microbiome Analysis of Carious Lesions in Pre-School Children with Early Childhood Caries and Congenital Heart Disease.

Nelly Schulz-Weidner, Markus Weigel, Filip Turujlija, Kassandra Komma, Jan Philipp Mengel, Maximiliane Amelie Schlenz, Julia Camilla Bulski, Norbert Krämer, Torsten Hain

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Nelly Schulz-WeidnerDental Clinic-Department of Pediatric Dentistry, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, Germany.ORCID 0000-0003-4562-8232
Markus WeigelInstitute of Medical Microbiology, Justus Liebig University, Schubertstrasse 81, 35392 Giessen, Germany.ORCID 0000-0002-3140-3174
Filip TurujlijaInstitute of Medical Microbiology, Justus Liebig University, Schubertstrasse 81, 35392 Giessen, Germany.
Kassandra KommaInstitute of Medical Microbiology, Justus Liebig University, Schubertstrasse 81, 35392 Giessen, Germany.
Jan Philipp MengelInstitute of Medical Microbiology, Justus Liebig University, Schubertstrasse 81, 35392 Giessen, Germany.
Maximiliane Amelie SchlenzDental Clinic-Department of Prosthodontics, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, Germany.ORCID 0000-0003-4747-824X
Julia Camilla BulskiDental Clinic-Department of Pediatric Dentistry, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, Germany.ORCID 0000-0003-4145-6904
Norbert KrämerDental Clinic-Department of Pediatric Dentistry, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, Germany.
Torsten HainInstitute of Medical Microbiology, Justus Liebig University, Schubertstrasse 81, 35392 Giessen, Germany.
Justus-Liebig-Universität Gießen · DE

Funding

Deutsche Forschungsgemeinschaft KFO 309 Z01Deutsche Forschungsgemeinschaft SFB1021 Z02Deutsche Forschungsgemeinschaft SFB-TR84 B08HMWK LOEWE Research Cluster Diffusible Signals B3
6 · The paper itself

Abstract

Oral bacteria have been associated with several systemic diseases. Moreover, the abundance of bacteria associated with caries has been found to be higher in patients with congenital heart disease (CHD) than in healthy control groups (HCGs). Therefore, this study aimed to evaluate the dental microbiota in children with CHD compared to a HCG. The aim was to describe and compare the carious microbiome regarding the composition, diversity, and taxonomic patterns in these two groups. Twenty children with CHD and a HCG aged between two and six years participated. All of them were affected by early childhood caries. Microbiome profiling indicated that

Indexed as

16S rRNA genecongenital heart diseasedentinal microbiomedysbiosisearly childhood cariesmicrobiotanext-generation sequencingoral healthpediatric dentistry

Identifiers

PMID34576799
PMCPMC8469307
OpenAlexW3198715231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.