Evidence map›Paper›PMID 34576738›Full record

ArticleMicroorganisms2021

Lactic Acid Bacteria Exert a Hepatoprotective Effect against Ethanol-Induced Liver Injury in HepG2 Cells.

Ji Yeon Lee, Hyemin Kim, Yulah Jeong, Chang-Ho Kang

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Gut Microbiota and Its Metabolite Taurine-International journal of molecular sciences · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Heat-KilledNutrients · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Microorganisms · 2022
    Article
  19. Protective Effect ofMicroorganisms · 2022
    Article
  20. Nutrients · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ji Yeon LeeMEDIOGEN, Co., Ltd., Biovalley 1-ro, Jecheon-si 27159, Korea.ORCID 0000-0002-3622-7392
Hyemin KimMEDIOGEN, Co., Ltd., Biovalley 1-ro, Jecheon-si 27159, Korea.ORCID 0000-0002-3696-6726
Yulah JeongMEDIOGEN, Co., Ltd., Biovalley 1-ro, Jecheon-si 27159, Korea.ORCID 0000-0002-1187-6927
Chang-Ho KangMEDIOGEN, Co., Ltd., Biovalley 1-ro, Jecheon-si 27159, Korea.ORCID 0000-0001-6466-8550

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcoholic liver fatty disease (ALFD) is caused by excessive and chronic alcohol consumption. Alcohol consumption causes an imbalance in the intestinal microflora, leading to liver disease induced by the excessive release of endotoxins into the hepatic portal vein. Therefore, research on the intestinal microflora to identify treatments for ALFD is increasing. In this study, the protective effects of lactic acid bacteria (LAB) strains, including

Indexed as

alcoholCYP2E1hepatoprotectiveoxidative stressprobiotics

Identifiers

PMID34576738
PMCPMC8465258
OpenAlexW3198826589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.