Evidence map›Paper›PMID 34576686›Full record

ArticleMaterials (Basel, Switzerland)2021

Raman Spectroscopy as a Novel Method for the Characterization of Polydioxanone Medical Stents Biodegradation.

Jan Loskot, Daniel Jezbera, Aleš Bezrouk, Rafael Doležal, Rudolf Andrýs, Vendula Francová, Dominik Miškář, Alena Myslivcová Fučíková

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jan LoskotDepartment of Physics, University of Hradec Králové, Rokitanského 62, 500 03 Hradec Králové, Czech Republic.ORCID 0000-0003-0172-4353
Daniel JezberaDepartment of Physics, University of Hradec Králové, Rokitanského 62, 500 03 Hradec Králové, Czech Republic.
Aleš BezroukDepartment of Medical Biophysics, Faculty of Medicine in Hradec Králové, Charles University, 500 03 Hradec Králové, Czech Republic.ORCID 0000-0002-2397-3847
Rafael DoležalDepartment of Chemistry, University of Hradec Králové, Rokitanského 62, 500 03 Hradec Králové, Czech Republic.
Rudolf AndrýsDepartment of Chemistry, University of Hradec Králové, Rokitanského 62, 500 03 Hradec Králové, Czech Republic.
Vendula FrancováELLA-CS, s.r.o., Milady Horákové 504/45, 500 06 Hradec Králové, Czech Republic.
Dominik MiškářDepartment of Physics, University of Hradec Králové, Rokitanského 62, 500 03 Hradec Králové, Czech Republic.
Alena Myslivcová FučíkováDepartment of Biology, University of Hradec Králové, Rokitanského 62, 500 03 Hradec Králové, Czech Republic.ORCID 0000-0001-9669-2854
University of Hradec Králové · CZCharles University · CZElla-Cs (Czechia) · CZ

Funding

Univerzita Hradec Králové Specific research project 2107/2021
6 · The paper itself

Abstract

Polydioxanone (PPDX), as an FDA approved polymer in tissue engineering, is an important component of some promising medical devices, e.g., biodegradable stents. The hydrolytic degradation of polydioxanone stents plays a key role in the safety and efficacy of treatment. A new fast and convenient method to quantitatively evaluate the hydrolytic degradation of PPDX stent material was developed. PPDX esophageal stents were degraded in phosphate-buffered saline for 24 weeks. For the first time, the changes in Raman spectra during PPDX biodegradation have been investigated here. The level of PPDX hydrolytic degradation was determined from the Raman spectra by calculating the area under the 1732 cm

Indexed as

biodegradable polymercrack growthhydrolytic degradationpolydioxanoneRaman spectrumstent

Identifiers

PMID34576686
PMCPMC8467320
OpenAlexW3200798381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.