ReviewMaterials (Basel, Switzerland)2021
Bioactive Glass Applications: A Literature Review of Human Clinical Trials.
Review in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Clinical efficacy of bioactive glass in periodontal regeneration: a systematic review and meta-analysis.Odontology · 2026Pooled it
- A systematic review on bioactive glass as a treatment for limb osteomyelitis and infected nonunion.Bone & joint open · 2025Pooled it
- Bioactive glass for periodontal regeneration: a systematic review.BMC oral health · 2023Pooled it
- pH-neutralization strategy to suppress GPCR68 spatiotemporally activates T cells and enhances anti-tumor immunity.Bioactive materials · 2026Article
- Article
- Mesoporous Bioactive Glass: Preparation, Characterisation, and Emerging Applications in Regenerative Medicine and Dentistry.International dental journal · 2026Review
- Bioactive restorative materials in dentistry: a comprehensive review of mechanisms, clinical applications, and future directions.Odontology · 2026Review
- Magnesium and Strontium-Doped Bioglass Nanoparticles as a Novel Formulation: Advancing Osteoconductivity and Enhancing Bone Healing Potential.Small science · 2026Article
- ZIF-8 functionalized PCL/BG composite scaffolds with improved bioactivity and osteogenic differentiation.Scientific reports · 2026Article
- A Borophosphate Glass Doped with Cobalt Oxide Improves Skeletal Muscle Structure and Function in Myopathic Mice.Journal of functional biomaterials · 2026Article
- Bioactive glass nanoparticles induce pronounced cytotoxicity in human hepatocellular carcinoma Hep-G2 cells through ROS-mediated genomic instability and mitochondrial apoptosis.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Bioactive glass nanoparticles induce strong preferential cytotoxicity and excessive ROS-mediated oxidative stress and apoptotic genomic DNA damage in non-small lung cancer cells.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Bioactive glass nanoparticles induce intrinsic p53-dependent apoptosis and promote genomic instability via ROS overproduction and mitochondrial depolarization in triple-negative breast cancer cells.Scientific reports · 2026Article
- TREATMENT OF BENIGN LYTIC BONE LESIONS WITH 45S5 BIOACTIVE GLASS: A CASE SERIES.Acta ortopedica brasileira · 2026Article
- Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery.Advanced healthcare materials · 2026Review
- Evidence of chronic sinusitis alleviation after open sinus allogeneic bone augmentation with simultaneous implant placement: A long-term retrospective observational study.Oral and maxillofacial surgery · 2025Observational
- Beyond Bioactive Glass Composition: Using Morphology to Improve In Vitro and In Vivo Performance.Advanced healthcare materials · 2025Review
- The Impact of Calcination on the Structure, Bioactivity, and Biocompatibility of Sol-Gel-Derived Glasses.ACS omega · 2025Article
- The Assessment of Bioactivity and Biological Responsiveness in Bioactive Glasses and Ceramics: A Review of Available Techniques.Materials (Basel, Switzerland) · 2025Review
- Impact of 45S5-Bioactive Glass on Chondrocytes in Knee Osteoarthritis-In Vitro Study Exploring Cellular Responses.Journal of functional biomaterials · 2025Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of bioactive glasses in dentistry, reconstructive surgery, and in the treatment of infections can be considered broadly beneficial based on the emerging literature about the potential bioactivity and biocompatibility of these materials, particularly with reference to Bioglass
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.