Evidence map›Paper›PMID 34576538›Full record

ArticleMaterials (Basel, Switzerland)2021

Functionality of Silk Cocoon (

Wei-Hsun Wang, Wen-Shin Lin, Chia-Hung Shih, Cheng-You Chen, Siao-Hong Kuo, Wei-Lin Li, Yung-Sheng Lin

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. ACS sustainable chemistry & engineering · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Sericin Protein: Structure, Properties, and Applications.Journal of functional biomaterials · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Heliyon · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wei-Hsun WangDepartment of Orthopaedics, Changhua Christian Hospital, Changhua 500209, Taiwan.
Wen-Shin LinDepartment of Plant Industry, National Pingtung University of Science and Technology, Pingtung 912301, Taiwan.ORCID 0000-0003-2671-4522
Chia-Hung ShihDepartment of Chemical Engineering, National United University, Miaoli 360001, Taiwan.
Cheng-You ChenPh.D. Program in Materials and Chemical Engineering, National United University, Miaoli 360001, Taiwan.
Siao-Hong KuoDepartment of Chemical Engineering, National United University, Miaoli 360001, Taiwan.
Wei-Lin LiDepartment of Chemical Engineering, National United University, Miaoli 360001, Taiwan.
Yung-Sheng LinDepartment of Chemical Engineering, National United University, Miaoli 360001, Taiwan.ORCID 0000-0002-9522-1812
National United University · TWNational Pingtung University of Science and Technology · TW

Funding

Ministry of Science and Technology, Taiwan 110-2622-E-239-003
6 · The paper itself

Abstract

Sericin, a textile waste, can be used for antioxidant and skin-whitening purposes. The hydrothermal method of extracting sericin is more eco-friendly than are chemical and enzymatic methods. In this study, silk cocoons were cut into pieces and then subjected to hydrothermal extraction at three temperatures (160, 200, and 220 °C) to obtain sericin extracts (Sericin160, Sericin200, and Sericin220, respectively). Antioxidant activity and tyrosinase inhibition were measured to determine the extracts' effectiveness. Sericin220 was the strongest antioxidant, with total phenol content, total flavonoid content, and ferric reducing power of 62.19 ± 0.04 mg gallic acid equivalents/g dry weight, 0.07 ± 0.01 mg quercetin equivalent/g dry weight, and 181.49 ± 0.024 mg vitamin C equivalent/g dry weight, respectively. The half-maximal inhibitory concentrations for DPPH and ABTS free-radical scavenging ability were 6.41 ± 0.05 and 0.79 ± 0.37 mg/mL, respectively. Sericin220 also exhibited the highest tyrosinase inhibition activity (70.82 ± 4.1 mg vitamin C equivalent/g), indicating its whitening potential.

Indexed as

antioxidantcocoonextracthydrothermalsericintyrosinase

Identifiers

PMID34576538
PMCPMC8468092
OpenAlexW3201033407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.