ArticleMaterials (Basel, Switzerland)2021
Cytotoxic and Genotoxic Effects of Composite Resins on Cultured Human Gingival Fibroblasts.
Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Biological effects of dental resin composites on human gingival fibroblasts: a systematic review of in vitro evidence.Clinical oral investigations · 2026Pooled it
- Biological Safety of 3D Printing Materials Based on Acrylic Resins Used in Dentistry: Narrative Review.Materials (Basel, Switzerland) · 2026Review
- Effect of Mouthwashes on the Mechanical Properties and Color Stability of Composite Material.Materials (Basel, Switzerland) · 2026Article
- The Biocompatibility and Cellular Response of Geristore in Comparison With Different Glass Ionomer Materials on Human Gingival Fibroblast Cells: A Comparative Study on Deep Marginal Elevation.International journal of biomaterials · 2026Article
- In vitro assessment of cytotoxic, genotoxic, and antimicrobial properties of pediatric restorative dental materials.BMC oral health · 2025Article
- Activation of Inflammatory and Apoptosis Pathways on Human Gingival Fibroblasts Exposed to Dental Resin Composites.Polymers · 2025Article
- Article
- Histological Evaluation of Polyacid-Modified Composite Resin and Conventional Composite Resin Used for Primary Molars Restoration.Dentistry journal · 2024Article
- Influence of Polymerization Protocol on Adhesion and Proliferation ofBiomedicines · 2024Article
- Mechanistic study of the stabilization of dentin-bonded restorative interfaces via collagen reinforcement by multi-acrylamides.Dental materials : official publication of the Academy of Dental Materials · 2024Article
- Polishing methods for composites restoration: the influence on human gingival fibroblasts behaviour.BMC oral health · 2024Article
- Article
- In Vitro Evaluation ofMaterials (Basel, Switzerland) · 2023Article
- Morpho-Functional Effect of a New Collagen-Based Medical Device on Human Gingival Fibroblasts: An In Vitro Study.Biomedicines · 2023Article
- Conditional Mitigation of Dental-Composite Material-Induced Cytotoxicity by Increasing the Cure Time.Journal of functional biomaterials · 2023Article
- Emerging Effects of Resveratrol Derivatives in Cells Involved in Oral Wound Healing: A Preliminary Study.International journal of molecular sciences · 2023Article
- Article
- Wear Properties of Conventional and High-Translucent Zirconia-Based Materials.Materials (Basel, Switzerland) · 2022Article
- Biodegradation of Dental Resin-Based Composite-A Potential Factor Affecting the Bonding Effect: A Narrative Review.Biomedicines · 2022Review
- The Retention Effect of Resin-Based Desensitizing Agents on Hypersensitivity-A Randomized Controlled Trial.Materials (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 1 institution in 1 country.
Funding
Abstract
The aim of the study was to evaluate the cytotoxic and genotoxic potential of five commercially available dental composite resins (CRs), investigating the effect of their quantifiable bisphenol-A-glycidyl-methacrylate (Bis-GMA) and/or triethylene glycol dimethacrylate (TEGDMA) release. Experiments were performed using the method of soaking extracts, which were derived from the immersion of the following CRs in the culture medium: Clearfil-Majesty-ES-2, GrandioSO, and Enamel-plus-HRi (Bis-GMA-based); Enamel-BioFunction and VenusDiamond (Bis-GMA-free). Human Gingival Fibroblasts (hGDFs) were employed as the cellular model to mimic in vitro the oral cavity
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.