Evidence map›Paper›PMID 34576426›Full record

ArticleMaterials (Basel, Switzerland)2021

A Diamond-Based Dose-per-Pulse X-ray Detector for Radiation Therapy.

Sara Pettinato, Marco Girolami, Riccardo Olivieri, Antonella Stravato, Cristina Caruso, Stefano Salvatori

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Structural and Photoelectronic Properties of κ-GaMaterials (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sara PettinatoEngineering Faculty, Niccolò Cusano University, Via don Carlo Gnocchi 3, 00166 Rome, Italy.
Marco GirolamiIstituto di Struttura della Materia, Consiglio Nazionale delle Ricerche (ISM-CNR), Strada Provinciale 35D 9, Montelibretti, 00010 Rome, Italy.ORCID 0000-0003-0063-3636
Riccardo OlivieriAzienda Ospedaliera "San Giovanni-Addolorata", 00184 Rome, Italy.
Antonella StravatoAzienda Ospedaliera "San Giovanni-Addolorata", 00184 Rome, Italy.
Cristina CarusoAzienda Ospedaliera "San Giovanni-Addolorata", 00184 Rome, Italy.
Stefano SalvatoriEngineering Faculty, Niccolò Cusano University, Via don Carlo Gnocchi 3, 00166 Rome, Italy.
Azienda Ospedaliera San Giovanni Addolorata · ITInstitute of Structure of Matter · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the goals of modern dynamic radiotherapy treatments is to deliver high-dose values in the shortest irradiation time possible. In such a context, fast X-ray detectors and reliable front-end readout electronics for beam diagnostics are crucial to meet the necessary quality assurance requirements of care plans. This work describes a diamond-based detection system able to acquire and process the dose delivered by every single pulse sourced by a linear accelerator (LINAC) generating 6-MV X-ray beams. The proposed system is able to measure the intensity of X-ray pulses in a limited integration period around each pulse, thus reducing the inaccuracy induced by unnecessarily long acquisition times. Detector sensitivity under 6-MV X-photons in the 0.1-10 Gy dose range was measured to be 302.2 nC/Gy at a bias voltage of 10 V. Pulse-by-pulse measurements returned a charge-per-pulse value of 84.68 pC, in excellent agreement with the value estimated (but not directly measured) with a commercial electrometer operating in a continuous integration mode. Significantly, by intrinsically holding the acquired signal, the proposed system enables signal processing even in the millisecond period between two consecutive pulses, thus allowing for effective real-time dose-per-pulse monitoring.

Indexed as

CVD diamondgated integratorLINACpulsed-mode charge measurementsX-ray detectors

Identifiers

PMID34576426
PMCPMC8466252
OpenAlexW3200119057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.