Evidence map›Paper›PMID 34576415›Full record

ArticleMaterials (Basel, Switzerland)2021

Independent Lung Ventilation-Experimental Studies on a 3D Printed Respiratory Tract Model.

Katarzyna Kramek-Romanowska, Anna M Stecka, Krzysztof Zieliński, Agata Dorosz, Piotr Okrzeja, Marcin Michnikowski, Marcin Odziomek

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Katarzyna Kramek-RomanowskaNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Ks Trojdena 4, 02-109 Warsaw, Poland.ORCID 0000-0001-9969-0360
Anna M SteckaNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Ks Trojdena 4, 02-109 Warsaw, Poland.
Krzysztof ZielińskiNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Ks Trojdena 4, 02-109 Warsaw, Poland.ORCID 0000-0002-2055-4006
Agata DoroszFaculty of Chemical and Process Engineering, Warsaw University of Technology, Waryńskiego 1, 00-645 Warsaw, Poland.
Piotr OkrzejaNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Ks Trojdena 4, 02-109 Warsaw, Poland.
Marcin MichnikowskiNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Ks Trojdena 4, 02-109 Warsaw, Poland.
Marcin OdziomekFaculty of Chemical and Process Engineering, Warsaw University of Technology, Waryńskiego 1, 00-645 Warsaw, Poland.ORCID 0000-0002-4806-341X
Institute of Biocybernetics and Biomedical Engineering · PLWarsaw University of Technology · PL

Funding

Narodowe Centrum Badań i Rozwoju LIDER/19/0107/L-8/16/NCBR/2017
6 · The paper itself

Abstract

Independent lung ventilation (ILV) is a life-saving procedure in unilateral pulmonary pathologies. ILV is underused in clinical practice, mostly due to the technically demanding placement of a double lumen endotracheal tube (ETT). Moreover, the determination of ventilation parameters for each lung in vivo is limited. In recent years, the development of 3D printing techniques enabled the production of highly accurate physical models of anatomical structures used for in vitro research, considering the high risk of in vivo studies. The purpose of this study was to assess the influence of double-lumen ETT on the gas transport and mixing in the anatomically accurate 3D-printed model of the bronchial tree, with lung lobes of different compliances, using various ventilation modes. The bronchial tree was obtained from Respiratory Drug Delivery (RDD Online, Richmond, VA, USA), processed and printed by a dual extruder FFF 3D printer. The test system was also composed of left side double-lumen endotracheal tube, Siemens Test Lung 190 and anesthetic breathing bag (as lobes). Pressure and flow measurements were taken at the outlets of the secondary bronchus. The measured resistance increased six times in the presence of double-lumen ETT. Differences between the flow distribution to the less and more compliant lobe were more significant for the airways with double-lumen ETT. The ability to predict the actual flow distribution in model airways is necessary to conduct effective ILV in clinical conditions.

Indexed as

3D-printed anatomical modelendotracheal tubeindependent lung ventilationlung compliancemechanical ventilationpulmonary flow

Identifiers

PMID34576415
PMCPMC8472474
OpenAlexW3197070945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.