Evidence map›Paper›PMID 34576279›Full record

ReviewInternational journal of molecular sciences2021

Synthesis and Application of Silica-Coated Quantum Dots in Biomedicine.

Xuan-Hung Pham, Seung-Min Park, Kyeong-Min Ham, San Kyeong, Byung Sung Son, Jaehi Kim, Eunil Hahm, Yoon-Hee Kim, Sungje Bock, Wooyeon Kim and 5 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Multimodal Magnetic Nanoparticle-Quantum Dot Composites.Nanomaterials (Basel, Switzerland) · 2025
    Article
  7. Advancing Cancer-Targeted Nanotherapies with Tumor Homing Peptides.ACS pharmacology & translational science · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Advanced Optical Materials: From Materials to Applications.International journal of molecular sciences · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xuan-Hung PhamDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.ORCID 0000-0002-4927-7102
Seung-Min ParkDepartment of Urology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Kyeong-Min HamDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
San KyeongSchool of Chemical and Biological Engineering, Seoul National University, Seoul 03080, Korea.
Byung Sung SonDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Jaehi KimDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Eunil HahmDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Yoon-Hee KimDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Sungje BockDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Wooyeon KimDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.
Seunho JungDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.ORCID 0000-0002-0801-9342
Sangtaek OhDepartment of Bio and Fermentation Convergence Technology, Kookmin University, Seoul 02707, Korea.
Sang Hun LeeDepartment of Chemical and Biological Engineering, Hanbat National University, Daejeon 34158, Korea.ORCID 0000-0002-8629-8842
Do Won HwangDepartment of Nuclear Medicine, College of Medicine, Seoul National University, Seoul 03080, Korea.
Bong-Hyun JunDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea.ORCID 0000-0001-6556-7946

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quantum dots (QDs) are semiconductor nanoparticles with outstanding optoelectronic properties. More specifically, QDs are highly bright and exhibit wide absorption spectra, narrow light bands, and excellent photovoltaic stability, which make them useful in bioscience and medicine, particularly for sensing, optical imaging, cell separation, and diagnosis. In general, QDs are stabilized using a hydrophobic ligand during synthesis, and thus their hydrophobic surfaces must undergo hydrophilic modification if the QDs are to be used in bioapplications. Silica-coating is one of the most effective methods for overcoming the disadvantages of QDs, owing to silica's physicochemical stability, nontoxicity, and excellent bioavailability. This review highlights recent progress in the design, preparation, and application of silica-coated QDs and presents an overview of the major challenges and prospects of their application.

Indexed as

AnimalsBiocompatible MaterialsBiological AvailabilityBiomarkers, TumorCadmiumCell Line, TumorHumansIn Vitro TechniquesMiceMice, Inbred BALB CMicellesNeoplastic Cells, CirculatingOptical ImagingPhenotypeQuantum DotsSerum Albumin, HumanBiocompatible MaterialsBiomarkers, TumorCadmiumMicellesSerum Albumin, HumanSilicon Dioxidebioapplicationquantum dot (QD)silica coatingsilica encapsulationsurface modification

Identifiers

PMID34576279
PMCPMC8468474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.