Evidence map›Paper›PMID 34576273›Full record

ArticleInternational journal of molecular sciences2021

Metabolic and Lipidomic Assessment of Kidney Cells Exposed to Nephrotoxic Vancomycin Dosages.

Simon Lagies, Roman Pichler, Georg Vladimirov, Jana Gawron, Fabian Bäzner, Annabell Schreiner, Dajana Kadena, Dietmar A Plattner, Soeren S Lienkamp, Bernd Kammerer

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Simon LagiesCentre for Integrative Signalling Analysis, University of Freiburg, 79104 Freiburg, Germany.ORCID 0000-0002-5245-1781
Roman PichlerDepartment of Medicine IV, Nephrology and Primary Care, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79110 Freiburg, Germany.ORCID 0000-0003-2602-998X
Georg VladimirovCentre for Integrative Signalling Analysis, University of Freiburg, 79104 Freiburg, Germany.ORCID 0000-0003-0056-8803
Jana GawronCentre for Integrative Signalling Analysis, University of Freiburg, 79104 Freiburg, Germany.
Fabian BäznerCentre for Integrative Signalling Analysis, University of Freiburg, 79104 Freiburg, Germany.ORCID 0000-0002-5826-3140
Annabell SchreinerCentre for Integrative Signalling Analysis, University of Freiburg, 79104 Freiburg, Germany.
Dajana KadenaCentre for Integrative Signalling Analysis, University of Freiburg, 79104 Freiburg, Germany.
Dietmar A PlattnerInstitute of Organic Chemistry, University of Freiburg, 79104 Freiburg, Germany.ORCID 0000-0003-3567-2117
Soeren S LienkampDepartment of Medicine IV, Nephrology and Primary Care, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79110 Freiburg, Germany.ORCID 0000-0003-2963-6865
Bernd KammererCentre for Integrative Signalling Analysis, University of Freiburg, 79104 Freiburg, Germany.
University of Freiburg · DE

Funding

European Research Council 804474Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 310030_189102
6 · The paper itself

Abstract

Vancomycin is a glycopeptide antibiotic used against multi-drug resistant gram-positive bacteria such as

Indexed as

LipidomicsAnimalsAnti-Bacterial AgentsChromatography, LiquidDogsDose-Response Relationship, DrugDrug Evaluation, PreclinicalGas Chromatography-Mass SpectrometryGlutathioneKidneyKidney Tubules, CollectingLipidsMadin Darby Canine Kidney CellsMass SpectrometryMetabolomicsMethicillin-Resistant Staphylococcus aureusAnti-Bacterial AgentsGlutathioneLipidsVancomycinGC/MSLC/MSlipidomicsmass spectrometrymetabolomicsnephrotoxicitytubulevancomycin

Identifiers

PMID34576273
PMCPMC8466248
OpenAlexW3201174518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.