Evidence map›Paper›PMID 34576264›Full record

ArticleInternational journal of molecular sciences2021

Cell-Penetrating Delivery of Nitric Oxide by Biocompatible Dinitrosyl Iron Complex and Its Dermato-Physiological Implications.

Yu-Chieh Chen, Yi-Hong Chen, Han Chiu, Yi-Hsuan Ko, Ruei-Ting Wang, Wei-Ping Wang, Yung-Jen Chuang, Chieh-Cheng Huang, Tsai-Te Lu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Oral Delivery Systems for Gasotransmitters in Therapeutic Applications.Polymer science & technology (Washington, D.C.) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yu-Chieh ChenDepartment of Medical Science & Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu 30013, Taiwan.ORCID 0000-0002-1838-276X
Yi-Hong ChenInstitute of Biomedical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.ORCID 0000-0002-0901-5597
Han ChiuInstitute of Biomedical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.
Yi-Hsuan KoDepartment of Medical Science & Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu 30013, Taiwan.
Ruei-Ting WangCHLITINA Research and Development Center, CHLITINA Holding Ltd., Taipei 10073, Taiwan.
Wei-Ping WangCHLITINA Research and Development Center, CHLITINA Holding Ltd., Taipei 10073, Taiwan.
Yung-Jen ChuangDepartment of Medical Science & Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu 30013, Taiwan.ORCID 0000-0002-6022-0107
Chieh-Cheng HuangInstitute of Biomedical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.ORCID 0000-0003-1773-8450
Tsai-Te LuInstitute of Biomedical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.ORCID 0000-0001-6977-2568
National Tsing Hua University · TW

Funding

Ministry of Science and Technology, Taiwan MOST 109-2628-M-007-003-MY3, MOST 109-2622-M-007-003-CC2, and MOST 110-2622-M-007-002National Tsing Hua University 109Q2711E1 and 110Q2711E1
6 · The paper itself

Abstract

After the discovery of endogenous dinitrosyl iron complexes (DNICs) as a potential biological equivalent of nitric oxide (NO), bioinorganic engineering of [Fe(NO)

Indexed as

AnimalsBiocompatible MaterialsCell LineCell MovementCell ProliferationCell SurvivalCollagenCorneaDrug Delivery SystemsEmbryo, NonmammalianEpitheliumEyeFibroblastsHumansIn Vitro TechniquesIronBiocompatible MaterialsCollagendinitrosyl iron complexIronNitric OxideNitrogen OxidesOxygencollagen depositioncontrolled deliverydinitrosyl iron complexnitric oxidewound healing

Identifiers

PMID34576264
PMCPMC8469893
OpenAlexW3199212515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.