Evidence map›Paper›PMID 34576124›Full record

ArticleInternational journal of molecular sciences2021

Therapeutic Effects of an Anti-sialyl Lewis X Antibody in a Murine Model of Allergic Asthma.

Wei Xiong, Wenxin Liu, Shogo Nishida, Daichi Komiyama, Wei Liu, Jotaro Hirakawa, Hiroto Kawashima

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wei XiongLaboratory of Microbiology and Immunology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan.ORCID 0000-0002-7861-5940
Wenxin LiuLaboratory of Microbiology and Immunology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan.
Shogo NishidaLaboratory of Microbiology and Immunology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan.
Daichi KomiyamaLaboratory of Microbiology and Immunology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan.
Wei LiuLaboratory of Microbiology and Immunology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan.
Jotaro HirakawaLaboratory of Microbiology and Immunology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan.
Hiroto KawashimaLaboratory of Microbiology and Immunology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 260-8675, Japan.ORCID 0000-0002-6599-7329
Chiba University · JP

Funding

Japan Agency for Medical Research and Development 20ae0101034h0005Japan Society for the Promotion of Science 15K18869Japan Society for the Promotion of Science 20H03379
6 · The paper itself

Abstract

Asthma is an allergic disease that causes severe infiltration of leukocytes into the lungs. Leukocyte infiltration is mediated by the binding of sialyl Lewis X (sLe

Indexed as

AnimalsAntibodies, MonoclonalAsthmaBone MarrowCell DifferentiationDisease Models, AnimalEosinophilsFemaleHypersensitivityImmunityLungMiceMice, Inbred C57BLModels, BiologicalProtein BindingP-SelectinAntibodies, MonoclonalP-SelectinSialyl Lewis X Antigenantibodyasthmadruggable targetsleukocyte infiltrationsialyl Lewis X

Identifiers

PMID34576124
PMCPMC8471066
OpenAlexW3199247878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.