Evidence map›Paper›PMID 34576118›Full record

ArticleInternational journal of molecular sciences2021

WGCNA Identifies Translational and Proteasome-Ubiquitin Dysfunction in Rett Syndrome.

Florencia Haase, Brian S Gloss, Patrick P L Tam, Wendy A Gold

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Florencia HaaseFaculty of Medicine and Health, School of Medical Science, The University of Sydney, Camperdown, NSW 2050, Australia.
Brian S GlossWestmead Research Hub, Westmead Institute for Medical Research, Westmead, NSW 2145, Australia.
Patrick P L TamFaculty of Medicine and Health, School of Medical Science, The University of Sydney, Camperdown, NSW 2050, Australia.
Wendy A GoldFaculty of Medicine and Health, School of Medical Science, The University of Sydney, Camperdown, NSW 2050, Australia.ORCID 0000-0003-1808-0646
The University of Sydney · AUWestmead Institute for Medical Research · AU

Funding

The Neil and Norma Hill Foundation CON204635
6 · The paper itself

Abstract

Rett Syndrome (RTT) is an X linked neurodevelopmental disorder caused by mutations in the methyl-CpG-binding protein 2 (

Indexed as

Gene Regulatory NetworksCluster AnalysisDatabases, GeneticFibroblastsGene Expression RegulationHumansInduced Pluripotent Stem CellsMethyl-CpG-Binding Protein 2NeuronsPrincipal Component AnalysisProteasome Endopeptidase ComplexProtein BiosynthesisProtein DomainsRett SyndromeUbiquitinMethyl-CpG-Binding Protein 2Proteasome Endopeptidase ComplexUbiquitiniPSCsRTTWGCNA

Identifiers

PMID34576118
PMCPMC8465861
OpenAlexW3199723092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.