Evidence map›Paper›PMID 34575934›Full record

ArticleInternational journal of molecular sciences2021

The Anti-Atherosclerotic Action of FFAR4 Agonist TUG-891 in ApoE-Knockout Mice Is Associated with Increased Macrophage Polarization towards M2 Phenotype.

Anna Kiepura, Kamila Stachyra, Anna Wiśniewska, Katarzyna Kuś, Klaudia Czepiel, Maciej Suski, Magdalena Ulatowska-Białas, Marcin Surmiak, Rafał Olszanecki

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. FFAR4 Deficiency Increases Necrotic Cores in Advanced Lesions of ApoEArteriosclerosis, thrombosis, and vascular biology · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Anna KiepuraChair of Pharmacology, Faculty of Medicine, Jagiellonian University Medical College, 16 Grzegorzecka Street, 31-531 Cracow, Poland.ORCID 0000-0002-3513-7221
Kamila StachyraChair of Pharmacology, Faculty of Medicine, Jagiellonian University Medical College, 16 Grzegorzecka Street, 31-531 Cracow, Poland.ORCID 0000-0003-1817-129X
Anna WiśniewskaChair of Pharmacology, Faculty of Medicine, Jagiellonian University Medical College, 16 Grzegorzecka Street, 31-531 Cracow, Poland.
Katarzyna KuśChair of Pharmacology, Faculty of Medicine, Jagiellonian University Medical College, 16 Grzegorzecka Street, 31-531 Cracow, Poland.ORCID 0000-0001-6107-0115
Klaudia CzepielChair of Pharmacology, Faculty of Medicine, Jagiellonian University Medical College, 16 Grzegorzecka Street, 31-531 Cracow, Poland.
Maciej SuskiChair of Pharmacology, Faculty of Medicine, Jagiellonian University Medical College, 16 Grzegorzecka Street, 31-531 Cracow, Poland.ORCID 0000-0001-7575-2184
Magdalena Ulatowska-BiałasDepartment of Pathomorphology, Jagiellonian University Medical College, 16 Grzegorzecka Street, 31-531 Cracow, Poland.
Marcin SurmiakDepartment of Internal Medicine, Faculty of Medicine, Jagiellonian University Medical College, 8 Skawińska Street, 31-066 Kraków, Poland.
Rafał OlszaneckiChair of Pharmacology, Faculty of Medicine, Jagiellonian University Medical College, 16 Grzegorzecka Street, 31-531 Cracow, Poland.
Jagiellonian University · PL

Funding

Narodowym Centrum Nauki NCN;2017/25/N/NZ3/02943
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBiomarkersBiphenyl CompoundsBody WeightCell PlasticityImmunophenotypingInflammation MediatorsLipidsMacrophage ActivationMacrophagesMiceMice, KnockoutMice, Knockout, ApoEPhenotypePhenylpropionatesReceptors, G-Protein-Coupled3-(4-((4-fluoro-4'-methyl-(1,1'-biphenyl)-2-yl)methoxy)phenyl)propanoic acidBiomarkersBiphenyl CompoundsFFAR4 protein, mouseInflammation MediatorsLipidsPhenylpropionatesReceptors, G-Protein-CoupledapoE-knockout miceatherosclerosisFFAR4free fatty acid receptorsinflammationmacrophages

Identifiers

PMID34575934
PMCPMC8471331
OpenAlexW3198843245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.